GIT1 protects against breast cancer growth through negative regulation of Notch

Songbai Zhang, Ayako Miyakawa, Malin Wickström, Cecilia Dyberg, Lauri Louhivuori, Manuel Varas-godoy, Kati Kemppainen, Shigeaki Kanatani, Dagmara Kaczynska, Ivar Dehnisch Ellström, Lotta Elfman, Pauliina Kronqvist, Heli Repo, Katsuhiko Mikoshiba, Cecilia Sahlgren, John Inge Johnsen, Per Uhlén^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

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Notch counteracts replication stress to prevent cancer cell senescence
Sahlgren, C.
Cancer Foundation Finland, Sigrid Jusélius Foundation
01/05/20 → 31/12/23
Project: Foundation
AKT-mediated post-translational regulation of NOTCH3 – decoding the Notch phosphorylation switchboard for targeted therapies in cancer
Sahlgren, C.
01/09/19 → 30/09/22
Project: Foundation
CellMech: Center of Excellence in Cellular Mechanostasis
Sahlgren, C., Sistonen, L., Eriksson, J., Toivola, D., Meinander, A., Cheng, F. & Jacquemet, G.
01/03/19 → 29/02/24
Project: Foundation
Notch4/14-3-3 interaction in breast cancer and small molecule stabilizers as novel opportunities for breast cancer therapeutics
Sahlgren, C.
01/01/19 → 31/12/20
Project: Foundation
PESCADoR: Phenotypic Screening for Cancer Drug Discovery
Nees, M., Rosenholm, J. & Sahlgren, C.
01/09/17 → 31/08/21
Project: Research Council of Finland/Other Research Councils
Unraveling the interplay between ECM stiffness and topography, Jagged-Notch signaling and tumor invasiveness
Sahlgren, C.
01/05/17 → 30/04/20
Project: Foundation
Regulation of Notch3 by Pim Kinases – Novel Possibilities for Notch Targeted Therapy in Breast Cancer
Sahlgren, C.
01/09/16 → 30/09/18
Project: Foundation