Research output per year
Research output per year
The PESCADoR consortium aims to combine complementary local expertise to develop a high content, phenotypic screening or "fishing" platform that fully recapitulates the complexity of solid human cancers. We will provide matching, well characterised tools for cost-effective and fast pre-clinical drug discovery and chemosensitivity testing, based on living microtissues.
This consortium aims to develop an experimental platform that recapitulates the architecture of human cancers. Three-dimensional “spheroid” cultures, lab-on-a-chip, so-called microfluidics and 3D bioprinting solutions have already contributed to physiologically much more relevant model systems – compared to standard two-dimensional monolayer cultures. However, such models are not yet more predictive for the outcome of treatment in clinical practice! There is still a high demand for better models that recapitulate or mimic the response of functional and living tissues, not just single cells, to anti-cancer therapies. Ideally, better platforms for testing anti-cancer therapies should also provide a possibility for fast microscopic imaging. This imaging-based evaluation of drug effects is entirely based on structural information. With a platform like this, we can not only test drugs, but also means to specifically deliver compounds to the cancer cells.Short title | PESCADoR |
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Acronym | PESCADoR |
Status | Finished |
Effective start/end date | 01/09/17 → 31/08/21 |
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Research output: Contribution to journal › Article › Scientific › peer-review
Research output: Contribution to journal › Article › Scientific › peer-review
Research output: Contribution to journal › Article › Scientific › peer-review
Kałafut, J., Czapiński, J., Przybyszewska-Podstawka, A., Czerwonka, A., Odrzywolski, A., Sahlgren, C. & Rivero Müller, A.
20/05/22
1 Media contribution
Press/Media: Social Media Activity/Appearance
Sahlgren, C., Landor, S., Santio, N. M. & Koskinen, P. J.
22/04/21
1 Media contribution
Press/Media
Sahlgren, C., Koskinen, P. J., Santio, N. M. & Landor, S.
22/04/21
1 Media contribution
Press/Media