Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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NAP4DIVE: Non-Animal Platform for Nanoparticle-Based Delivery Across the Blood-Brain Barrier Interface with Vehicle Evolution
Sahlgren, C. (Principal Investigator), Rosenholm, J. (Principal Investigator), Zhang, H. (Principal Investigator), Viitala, T. (Principal Investigator) & Lafond, S. (Principal Investigator)
01/01/25 → 31/12/28
Project: EU
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Replication stress-induced Notch1 phosphorylation mediates sustained cancer cell proliferation during DNA damage
Sahlgren, C. (Principal Investigator)
01/05/23 → 30/04/26
Project: Foundation
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Tumor-LN-oC: Tumor lymph node on a chip
Zergioti, I. (Principal Investigator), J. den Toonder, J. M. (Principal Investigator), Klinakis, A. (Principal Investigator), Sahlgren, C. (Principal Investigator) & Lendl, B. (Principal Investigator)
01/05/21 → 31/10/25
Project: EU
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SignalSheets: Multilayer mechanosignalling in vascular homeostasis
Sahlgren, C. (Principal Investigator)
01/09/20 → 31/08/24
Project: Research Council of Finland/Other Research Councils
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Notch counteracts replication stress to prevent cancer cell senescence
Sahlgren, C. (Principal Investigator)
Cancer Foundation Finland, Sigrid Jusélius Foundation
01/05/20 → 31/12/23
Project: Foundation
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Germline-specific RNA helicase DDX4 forms cytoplasmic granules in cancer cells and promotes tumor growth
Olotu, O., Koskenniemi, A.-R., Ma, L., Paramonov, V., Laasanen, S., Louramo, E., Bourgery, M., Lehtiniemi, T., Laasanen, S., Rivero-Müller, A., Löyttyniemi, E., Sahlgren, C., Westermarck, J., Ventelä, S., Visakorpi, T., Poutanen, M., Vainio, P., Mäkelä, J.-A. & Kotaja, N., 23 Jul 2024, In: Cell Reports. 43, 7, 32 p., 114430.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)10 Downloads (Pure) -
Surface Modification of Mesoporous Silica Nanoparticles as a Means to Introduce Inherent Cancer-Targeting Ability in a 3D Tumor Microenvironment
Prabhakar, N., Långbacka, E., Özliseli, E., Mattsson, J., Mahran, A., Suleymanova, I., Sahlgren, C., Rosenholm, J., Åkerfelt, M. & Nees, M., Sept 2024, In: Small Science. 4, 9, 12 p., 2400084.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)26 Downloads (Pure) -
A multiscale computational model of arterial growth and remodeling including Notch signaling
van Asten, J. G. M., Latorre, M., Karakaya, C., Baaijens, F. P. T., Sahlgren, C. M., Ristori, T., Humphrey, J. D. & Loerakker, S., Oct 2023, In: Biomechanics and modeling in mechanobiology. 22, 5, p. 1569-1588Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile5 Citations (Scopus)47 Downloads (Pure) -
An in vitro model of cancer invasion with heterogeneous ECM created with droplet microfluidics
Jouybar, M., Sleeboom, J., Vaezzadeh, E., Sahlgren, C. & den Toonder, J., 23 Nov 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 16 p., 1267021.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)22 Downloads (Pure) -
Directing cellular responses in a nanocomposite 3D matrix for tissue regeneration with nanoparticle-mediated drug delivery
Özliseli, E., Sanlidag, S., Süren, B., Mahran, A., Parikainen, M., Sahlgren, C. & Rosenholm, J., Dec 2023, In: Materials Today Bio. 23, 16 p., 100865.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)43 Downloads (Pure)
Datasets
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Data underlying the publication "Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress"
van Engeland, N. (Creator), Suarez Rodriguez, F. (Creator), Rivero Müller, A. (Creator), Ristori, T. (Creator), Duran, C. L. (Creator), Stassen, O. (Creator), Antfolk, D. (Creator), Driessen, R. (Creator), Ruohonen, S. (Creator), Ruohonen, S. T. (Creator), Nuutinen, S. (Creator), Savontaus, E. (Creator), Loerakker, S. (Creator), Bayless, K. J. (Creator), Sjöqvist, M. (Creator), Bouten, C. V. C. (Creator), Eriksson, J. (Creator), Sahlgren, C. (Creator), Driessen, R. C. H. (Creator), Ruohonen, S. (Creator), T. Ruohonen, S. (Creator), Nuutinen, S. (Creator), Loerakker, S. (Creator) & J. Bayless, K. (Creator), 4TU.ResearchData, 10 Sept 2020
DOI: 10.4121/12854801.v1, https://data.4tu.nl/articles/_/12854801
Dataset
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Data underlying the publication "Computational characterization of the dish-in-a-dish, a high yield culture platform for endothelial shear stress studies on the orbital shaker"
Driessen, R. (Creator), Zhao, F. (Creator), Hofmann, S. (Creator), Bouten, C. V. C. (Creator), Sahlgren, C. (Creator) & Stassen, O. (Creator), 4TU.ResearchData, 22 Jun 2020
DOI: 10.4121/uuid:817dbbc8-f3d7-4b91-b809-1ea25214bd3c
Dataset
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Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls"
Ristori, T. (Creator), Stassen, O. (Creator), Sahlgren, C. (Creator), Loerakker, S. (Creator) & Loerakker, S. (Creator), 4TU.ResearchData, 20 Oct 2020
DOI: 10.4121/12854297.v1, https://data.4tu.nl/articles/_/12854297
Dataset
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Data underlying the publication "Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress"
van Engeland, N. (Creator), Suarez Rodriguez, F. (Creator), Rivero-Müller, A. (Creator), Ristori, T. (Creator), Duran, C. L. (Creator), Stassen, O. M. J. A. (Creator), Antfolk, D. (Creator), Driessen, R. C. H. (Creator), Ruohonen, S. (Creator), T. Ruohonen, S. (Creator), Nuutinen, S. (Creator), Savontaus, E. (Creator), Loerakker, S. (Creator), J. Bayless, K. (Creator), Sjöqvist, M. (Creator), Bouten, C. V. C. (Creator), Eriksson, J. E. (Creator) & Sahlgren, C. (Creator), 4TU.ResearchData, 10 Sept 2020
DOI: 10.4121/12854801.v1
Dataset
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Computational code underlying the publication “Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting”
Tiemeijer, L. A. (Creator), Ristori, T. (Creator), Stassen, O. M. J. A. (Creator), Ahlberg, J. (Creator), de Bijl, J. J. J. (Creator), Chen, C. S. (Creator), Bentley, K. (Creator), Bouten, C. V. C. (Creator) & Sahlgren, C. M. (Creator), 4TU.ResearchData, 6 May 2022
DOI: 10.4121/19235793.v1, https://data.4tu.nl/articles/_/19235793/1
Dataset
Prizes
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ÅAU Chancellor’s Prize for best publication
Rosenholm, J. (Recipient), Peuhu, E. (Recipient), Eriksson, J. (Recipient) & Sahlgren, C. (Recipient), 2013
Prize
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Knight, First Class, of the Order of the White Rose of Finland (FWR K I)
Sahlgren, C. (Recipient), 2018
Prize: Honorary award
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Member of The Finnish Society of Sciences and Letters
Sahlgren, C. (Recipient), 2018
Prize: Honorary award
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Member of the Swedish Academy of Engineering Sciences in Finland
Sahlgren, C. (Recipient), 2017
Prize: Honorary award
Activities
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Forskarnatten
Hellsten, L. (Organiser), Sahlgren, C. (Participant), Österbacka, R. (Participant), Långbacka, U. (Participant), Törnroos-Remes, A. (Participant), Aalto, M. (Member of programme committee), Weckman, J.-K. (Participant), Jacquemet, G. (Participant), Huynh, T. P. (Participant), Fogde, A. (Participant), Andersson, J.-E. (Participant), Ringbom, A. (Participant), Runeberg, R. (Participant) & Lindfelt, M. (Participant)
24 Sept 2021Activity: Participating in or organising an event › Organising a conference, symposium or workshop
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Aboagora - FIRE
Sahlgren, C. (Participant), Ringbom, A. (Participant) & Hellsten, L. (Organiser)
19 Aug 2021Activity: Participating in or organising an event › Participating in a conference, workshop, ...
Press/Media
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Från sjukdom till hälsa i laboratoriet
Sahlgren, C. & Soto Véliz, D.
14/09/22
1 Media contribution
Press/Media
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"Cell chatter" critical for arterial thickening
van Asten, J. G. M., Ristori, T., Baaijens, F. P. T., Sahlgren, C. & Loerakker, S.
15/08/22
1 Media contribution
Press/Media
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Life through a mathematicians’ eye
Ristori, T., Soto Véliz, D., Lin, K.-L. & Sahlgren, C.
09/06/22
1 Media contribution
Press/Media
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OptoNotch: Using light to activate Notch signaling
Kałafut, J., Czapiński, J., Przybyszewska-Podstawka, A., Czerwonka, A., Odrzywolski, A., Sahlgren, C. & Rivero Müller, A.
20/05/22
1 Media contribution
Press/Media: Social Media Activity/Appearance
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INBLICK
Hellsten, L., Österbacka, R., Sahlgren, C., Runeberg, R., Ringbom, A. & Torsi, L.
12/11/21
1 Media contribution
Press/Media