Notch counteracts replication stress to prevent cancer cell senescence

Sahlgren, Cecilia (PI)

Status	Active
Effective start/end date	01/05/20 → 31/12/23

Funding

Cancer Foundation Finland: €50,000.00
Cancer Foundation Finland: €50,000.00
Sigrid Jusélius Foundation: €195,000.00

Keywords

Notch signaling
replication stress
cancer
cell senescence

2 Article
2 Review Article or Literature Review

Modulating epigenetic modifications for cancer therapy (Review)
Castro-Muñoz, L. J., Ulloa, E. V., Sahlgren, C., Lizano, M., De La Cruz-Hernández, E. & Contreras-Paredes, A., Mar 2023, In: Oncology Reports. 49, 3, 59.
Research output: Contribution to journal › Review Article or Literature Review › peer-review

Open Access
File
10 Citations (Scopus)

38 Downloads (Pure)
GIT1 protects against breast cancer growth through negative regulation of Notch
Zhang, S., Miyakawa, A., Wickström, M., Dyberg, C., Louhivuori, L., Varas-godoy, M., Kemppainen, K., Kanatani, S., Kaczynska, D., Ellström, I. D., Elfman, L., Kronqvist, P., Repo, H., Mikoshiba, K., Sahlgren, C., Johnsen, J. I. & Uhlén, P., 1 Dec 2022, In: Nature Communications. 13, 1, 1537.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
5 Citations (Scopus)

9 Downloads (Pure)
Optogenetic control of NOTCH1 signaling
Kałafut, J., Czapiński, J., Przybyszewska-Podstawka, A., Czerwonka, A., Odrzywolski, A., Sahlgren, C. & Rivero-Müller, A., Dec 2022, In: Cell Communication and Signaling. 20, 1, p. 67 67.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
5 Citations (Scopus)

48 Downloads (Pure)

OptoNotch: Using light to activate Notch signaling
Joanna Kałafut, Jakub Czapiński, Alicja Przybyszewska-Podstawka, Arkadiusz Czerwonka, Adrian Odrzywolski, Cecilia Sahlgren & Adolfo Rivero Müller
20/05/22
1 Media contribution
Press/Media: Social Media Activity/Appearance
Nya forskningsrön om regleringen av hormonell bröstcancer
Cecilia Sahlgren, Sebastian Landor, Niina M. Santio & Päivi J. Koskinen
22/04/21
1 Media contribution
Press/Media
New Research Data on the Regulation of Hormone-dependent Breast Cancer
Cecilia Sahlgren, Päivi J. Koskinen, Niina M. Santio & Sebastian Landor
22/04/21
1 Media contribution
Press/Media