Projects per year
Personal profile
Biography
Jessica Rosenholm has been focusing on drug delivery the past >20 years, ever since she started her MSc thesis project in Physical Chemistry on controlled release from mesoporous silica matrixes. Since then, she has co-authored over 200 publications mostly related to drug delivery and related biomedical applications of the materials developed within her research group. Her thesis work “Modular Design of Mesoporous Silica Materials: Towards Multifunctional Drug Delivery Systems” was awarded national and international prizes, e.g. the Akzo Nobel Nordic Research Prize 2009 for best doctoral thesis and research activity in colloid and surface science in the Nordic countries. Her research interests concern 1) the development of nanoformulations for a broad range of cargo, e.g. hydrophobic and hydrophilic drugs, biomolecules, and molecular imaging agents; 2) synthesis of composite nanostructures for attaining multifunctionality, e.g. nanoantibiotics; and 3) evaluation of the potential and applicability of the developed nanomedical agents for in vitro and in vivo drug delivery and biomedical imaging together with our cross-disciplinary collaborators. Currently, the BioNanoMaterials group is also involved in exploring other types of novel technologies such as microfluidics and 3D bioprinting e.g. for tissue engineering.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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NAP4DIVE: Non-Animal Platform for Nanoparticle-Based Delivery Across the Blood-Brain Barrier Interface with Vehicle Evolution
Sahlgren, C. (Principal Investigator), Rosenholm, J. (Co-Principal Investigator), Zhang, H. (Co-Principal Investigator), Viitala, T. (Co-Principal Investigator) & Lafond, S. (Co-Principal Investigator)
01/01/25 → 31/12/28
Project: EU
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Nordic Pharmaceutical Translation and Innovation
Rosenholm, J. (Principal Investigator), Viitala, T. (Co-Principal Investigator), Zhang, H. (Co-Principal Investigator), Salo-Ahen, O. (Co-Principal Investigator), Filppula, A. (Co-Principal Investigator), Wang, X. (Co-Principal Investigator), Bansal, K. (Co-Investigator), Kulkov, I. (Co-Investigator), Ameyaw Ahen, F. (Co-Investigator), Salminen, T. A. (Co-Principal Investigator), Airenne, T. (Co-Investigator), Lehtonen, J. (Co-Investigator), Södergård, B. (Co-Investigator) & Rosenberg, S. (Co-Investigator)
01/01/24 → 31/12/28
Project: Research
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MADNESS: Centre of Excellence in Materials-driven solutions for combatting antimicrobial resistance
Rosenholm, J. (Principal Investigator), Porres Paltor, I. (Co-Principal Investigator), Bansal, K. (Coordinator), Lafond, S. (Co-Principal Investigator), Uppstu, P. (Co-Principal Investigator), Viitala, T. (Co-Principal Investigator), Wang, X. (Co-Principal Investigator), Wilen, C.-E. (Co-Principal Investigator), Xu, C. (Co-Principal Investigator), Zhang, H. (Co-Principal Investigator), Lu, Z. (Co-Investigator), Verma, J. (Co-Investigator), Kumar, V. (Co-Investigator), Frejborg, F. (Co-Investigator), Wang, S. (Co-Investigator), Ran, M. (Co-Investigator), Ma, X. (Co-Investigator), Yang, W. (Co-Investigator), Liang, S. (Co-Investigator), Zhang, Y. (Co-Investigator), Fan, L. (Co-Investigator), Chen, Y. (Co-Investigator), Wang, L. (Co-Investigator), Zhuang, P. (Co-Investigator), Rajan Prakash, D. (Co-Investigator), Howaili, F. (Co-Investigator), Gulshan, R. (Co-Investigator), Yadav, D. (Co-Investigator), Pathak, C. (Co-Investigator), Mustafa, R. (Co-Investigator), Rostami, L. (Co-Investigator), Jafari Dargahlou, M. (Co-Investigator), Nygård, A. (Co-Investigator) & Manasut, P. (Co-Investigator)
01/01/24 → 31/12/28
Project: Foundation
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PII: Printed Intelligence Infrastructure
Toivakka, M. (Principal Investigator), Xu, C. (Co-Principal Investigator), Bobacka, J. (Co-Principal Investigator), Viitala, T. (Co-Principal Investigator), Rosenholm, J. (Co-Principal Investigator), Österbacka, R. (Co-Principal Investigator), Anttu, N. (Co-Principal Investigator), Huynh, T. P. (Co-Principal Investigator), Peltonen, J. (Co-Principal Investigator), Wang, X. (Co-Principal Investigator), Zhang, H. (Co-Principal Investigator) & Wilen, C.-E. (Co-Principal Investigator)
01/01/24 → 31/12/28
Project: Research Council of Finland/Other Research Councils
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NanoPET: Early detection of breast cancer lung metastasis with high precision using new nanoparticle-based PET imaging agents
Rosenholm, J. (Principal Investigator), Xiang-Guo, L. (Principal Investigator), Bakay, E. (Co-Investigator) & Zhuang, X. (Co-Investigator)
01/05/23 → 30/04/26
Project: Foundation
Publications
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3D printing of tailored veterinary dual-release tablets: a semi-solid extrusion approach for metoclopramide
Mathiyalagan, R., Westerlund, M., Mahran, A., Altunay, R., Suuronen, J., Palo, M., Nyman, J., Immonen, E., Rosenholm, J., Monaco, E. & Wang, X., 13 Feb 2025, In: RSC Pharmaceutics.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Decorin Expressed From Herpes Simplex Virus Vector Improves Oncolytic Efficacy in Lung Adenocarcinoma Cells
Frejborg, F., Palomäki, J., Kalke, K., Orpana, J., Koivisto, O., Paavilainen, H., Rosenholm, J. M., Zhang, H., Hukkanen, V. & Järveläinen, H., 13 Jan 2025, In: Proteoglycan Research. 3, 1, e70016.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Downloads (Pure) -
Microfluidics-enabled core/shell nanostructure assembly: Understanding encapsulation processes via particle characterization and molecular dynamics
Inam, W., Bhadane, R., Yan, J., Peurla, M., Salo-Ahen, O. M. H., Rosenholm, J. M. & Zhang, H., Apr 2025, In: Advances in Colloid and Interface Science. 338, 103400.Research output: Contribution to journal › Article › Scientific › peer-review
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Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss
Mustafa, R. A., Wang, J., Xun, M., Rosenholm, J. M., Wang, W., Shu, Y. & Zhang, H., 2025, In: Advanced Science. n/a, n/aResearch output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Regulating macrophage glucose metabolism homeostasis via mitochondrial rheostats by short fiber-microsphere scaffolds for bone repair
Zhuang, P., Chen, Y., Zhang, Y., Yang, W., Zuo, G., Rosenholm, J. M., Wang, Z., Wang, J., Cui, W. & Zhang, H., Jun 2025, In: Bioactive materials. 49, p. 399-417 19 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Datasets
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Design and assembly of core/shell nanostructures as investigated by microfluidics and molecular dynamics simulation_dataset_DLS_TEM_MD
Inam, W. (Creator), Bhadane, R. (Creator), Yan, J. (Creator), Peurla, M. (Creator), Salo-Ahen, O. (Creator), Rosenholm, J. (Creator) & Zhang, H. (Creator), Zenodo, 5 Apr 2024
DOI: 10.5281/zenodo.10931143, https://zenodo.org10931143
Dataset
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Cell Volume (3D) Correlative Microscopy Facilitated by Intra-Cellular Fluorescent Nanodiamonds as Multi-Modal Probes
Prabhakar, N. (Creator), Belevich, I. (Creator), Peurla, M. (Creator), Heiligenstein, X. (Creator), Chang, H.-C. (Creator), Sahlgren, C. (Creator), Jokitalo, E. (Creator) & Rosenholm, J. (Creator), Zenodo, 22 Dec 2020
DOI: 10.5281/zenodo.4384503, https://zenodo.org/record/4384503
Dataset
Prizes
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ÅAU Chancellor’s Prize for best publication
Rosenholm, J. (Recipient), Peuhu, E. (Recipient), Eriksson, J. (Recipient) & Sahlgren, C. (Recipient), 2013
Prize
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Knight, First Class, of the Order of the White Rose of Finland (FWR K I)
Rosenholm, J. (Recipient), 6 Dec 2022
Prize: Honorary award
Activities
- 5 Hosting an academic visitor
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Usama Jamshaid
Rosenholm, J. (Host) & Viitala, T. (Host)
1 Sept 2024 → 6 Dec 2024Activity: Hosting a visitor › Hosting an academic visitor
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Tooru Andoh
Rosenholm, J. (Host) & Li, X.-G. (Host)
28 Feb 2024 → 28 Feb 2025Activity: Hosting a visitor › Hosting an academic visitor
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Aryane Vigato
Rosenholm, J. (Host) & Viitala, T. (Host)
1 Sept 2022 → 31 Mar 2023Activity: Hosting a visitor › Hosting an academic visitor
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İlayda Özliseli
Rosenholm, J. (Host) & Özliseli, E. (Host)
15 Jun 2022 → 9 Sept 2022Activity: Hosting a visitor › Hosting an academic visitor
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Behice Süren
Rosenholm, J. (Host) & Özliseli, E. (Host)
25 Aug 2021 → 25 Aug 2022Activity: Hosting a visitor › Hosting an academic visitor