GIT1 protects against breast cancer growth through negative regulation of Notch

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• Finished

  Notch counteracts replication stress to prevent cancer cell senescence

  Sahlgren, C. (Principal Investigator)

  Cancer Foundation Finland, Sigrid Jusélius Foundation

  01/05/20 → 31/12/23

  Project: Foundation

• AKT-mediated post-translational regulation of NOTCH3 – decoding the Notch phosphorylation switchboard for targeted therapies in cancer

  Sahlgren, C. (Principal Investigator)

  01/09/19 → 30/09/22

  Project: Foundation

• CellMech: Center of Excellence in Cellular Mechanostasis

  Sahlgren, C. (Principal Investigator), Sistonen, L. (Principal Investigator), Eriksson, J. (Principal Investigator), Toivola, D. (Principal Investigator), Meinander, A. (Principal Investigator), Cheng, F. (Principal Investigator) & Jacquemet, G. (Principal Investigator)

  01/03/19 → 29/02/24

  Project: Foundation

• Notch4/14-3-3 interaction in breast cancer and small molecule stabilizers as novel opportunities for breast cancer therapeutics

  Sahlgren, C. (Principal Investigator)

  01/01/19 → 31/12/20

  Project: Foundation

• PESCADoR: Phenotypic Screening for Cancer Drug Discovery

  Nees, M. (Principal Investigator), Rosenholm, J. (Principal Investigator) & Sahlgren, C. (Principal Investigator)

  01/09/17 → 31/08/21

  Project: Research Council of Finland/Other Research Councils

• Unraveling the interplay between ECM stiffness and topography, Jagged-Notch signaling and tumor invasiveness

  Sahlgren, C. (Principal Investigator)

  01/05/17 → 30/04/20

  Project: Foundation

• Regulation of Notch3 by Pim Kinases – Novel Possibilities for Notch Targeted Therapy in Breast Cancer

  Sahlgren, C. (Principal Investigator)

  01/09/16 → 30/09/18

  Project: Foundation