1990 …2021

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Research interests

My research team at the Structural Bioinformatics Laboratory (SBL) focuses 3D structures of proteins and, particularly, utilizing 3D structures to predict and understand protein function. Our research on the molecular mechanism of infection, inflammation and cancer intertwines crystallography with computational modeling approaches. We aim to find out how proteins interact with other molecules and what is the structural basis for their ligand selectivity. The proteins we are working with are drug targets, off-targets, biomarkers of disease stages, biocatalysts or targets for diagnostics of disease.

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  • InFLAMES: Innovation Ecosystem based on the Immune System

    Takeda, A., Marjamäki, A., Roivainen, A., Hakanen, A., Hänninen, A., Sahlgren, C., Julkunen, I., Ivaska, J., Eriksson, J., Jorma, T., Rinne, J., Knuuti, J., Westermarck, J., Jyrki, H., Gidwani, K., Elima, K., Aires, L., Elo, L. L., Hollmen, M., Johnson, M. S., Salmi, M., Oresic, M., Poutanen, M., Kortelainen, M., Pentikäinen, O., Raitakari, O., Jaakkola, P., Salminen, P., Taimen, P., Vallittu, P., Rantakari, P., Mattila, P., Nuutila, P., He, Q., Lahesmaa, R., De Figueiredo, R., Jalkanen, S., Lönnberg, T., Soukka, T., Salminen, T. A., Veromaa, T., Lamminmäki, U., Launis, V., Peltola, V. & Xiang-Guo, L.

    01/07/2030/04/23

    Project: Research