Projects per year
Personal profile
Research interests
My research team at the Structural Bioinformatics Laboratory (SBL) focuses 3D structures of proteins and, particularly, utilizing 3D structures to predict and understand protein function. Our research on the molecular mechanism of infection, inflammation and cancer intertwines crystallography with computational modeling approaches. We aim to find out how proteins interact with other molecules and what is the structural basis for their ligand selectivity. The proteins we are working with are drug targets, off-targets, biomarkers of disease stages, biocatalysts or targets for diagnostics of disease.
Fingerprint
Dive into the research topics where Tiina A. Salminen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
-
InFLAMES: Innovation Ecosystem based on the Immune System
Takeda, A., Marjamäki, A., Roivainen, A., Hakanen, A., Hänninen, A., Sahlgren, C., Julkunen, I., Ivaska, J., Eriksson, J., Jorma, T., Rinne, J., Knuuti, J., Westermarck, J., Jyrki, H., Gidwani, K., Elima, K., Aires, L., Elo, L. L., Hollmen, M., Johnson, M. S., Salmi, M., Oresic, M., Poutanen, M., Kortelainen, M., Pentikäinen, O., Raitakari, O., Jaakkola, P., Salminen, P., Taimen, P., Vallittu, P., Rantakari, P., Mattila, P., Nuutila, P., He, Q., Lahesmaa, R., De Figueiredo, R., Jalkanen, S., Lönnberg, T., Soukka, T., Salminen, T. A., Veromaa, T., Lamminmäki, U., Launis, V., Peltola, V. & Xiang-Guo, L.
01/07/20 → 30/04/23
Project: Research
Publications
-
Conserved lysine residues in decorin binding proteins of Borrelia garinii are critical in adhesion to human brain microvascular endothelial cells
Pietikäinen, A., Åstrand, M., Cuellar, J., Glader, O., Elovaara, H., Rouhiainen, M., Salo, J., Furihata, T., Salminen, T. A. & Hytönen, J., 2021, (E-pub ahead of print) In: Molecular Microbiology.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion
Landor, S. K. J., Santio, N. M., Eccleshall, W. B., Paramonov, V. M., Gagliani, E. K., Hall, D., Jin, S-B., Dahlström, K. M., Salminen, T. A., Rivero-Müller, A., Lendahl, U., Kovall, R. A., Koskinen, P. J. & Sahlgren, C., 25 Mar 2021, (E-pub ahead of print) In: Journal of Biological Chemistry. 296Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile7 Downloads (Pure) -
A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community)
Orengo, C., Velankar, S., Wodak, S., Zoete, V., Bonvin, A. M. J. J., Elofsson, A., Feenstra, K. A., Gerloff, D. L., Hamelryck, T., Hancock, J. M., Helmer-Citterich, M., Hospital, A., Orozco, M., Perrakis, A., Rarey, M., Soares, C., Sussman, J. L., Thornton, J. M., Tuffery, P., Tusnady, G. & 3 others, , 2020, In: f1000research. 9, 278Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Candida antarctica Lipase A-Based Enantiorecognition of a Highly Strained 4-Dibenzocyclooctynol (DIBO) Used for PET Imaging
Sirén, S., Dahlström, K. M., Puttreddy, R., Rissanen, K., Salminen, T. A., Scheinin, M., Li, X-G. & Liljeblad, A., 17 Feb 2020, In: Molecules. 25, 4, 879.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
Evolution-guided engineering of non-heme iron enzymes involved in nogalamycin biosynthesis
Wandi, BN., Siitonen, V., Dinis, P., Vukic, V., Salminen, T. & Metsa-Ketela, M., 2020, In: FEBS Journal. 287, 14, p. 2998-3011 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
1 Citation (Scopus)