Projects per year
Personal profile
Research interests
Research focuses on development of methods for analysis and modeling of molecular structures.Expert in scientific IT; compute clusters and computational tools. Provides services and collaborates with Biocenter Finland technology platforms, particularly Biological imaging, Drug Discovery & Chemical Biology, Genome-wide methods, and Structural Biology.
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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Nordic Pharmaceutical Translation and Innovation
Rosenholm, J., Viitala, T., Zhang, H., Salo-Ahen, O., Filppula, A., Wang, X., Bansal, K., Kulkov, I., Ameyaw Ahen, F., Salminen, T. A., Airenne, T., Lehtonen, J., Södergård, B. & Rosenberg, S.
01/01/24 → 31/12/28
Project: Research
Publications
- 14 Article
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Virtual Screening Strategy to Identify Retinoic Acid-Related Orphan Receptor γt Modulators
Jokinen, E., Niemeläinen, M., Kurkinen, S., Lehtonen, J., Lätti, S., Postila, P., Pentikäinen, O. & Niinivehmas, S., 13 Apr 2023, In: Molecules. 28, 8, 20 p., 3420.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)4 Downloads (Pure) -
Ligand-Enhanced Negative Images Optimized for Docking Rescoring
Kurkinen, S., Lehtonen, J. V., Pentikäinen, O. & Postila, P., 17 Jul 2022, In: International Journal of Molecular Sciences. 23, 14Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)19 Downloads (Pure) -
Optimization of Cavity-Based Negative Images to Boost Docking Enrichment in Virtual Screening
Kurkinen, S. T., Lehtonen, J. V., Pentikäinen, O. T. & Postila, P. A., 28 Feb 2022, In: Journal of Chemical Information and Modeling. 62, 4, p. 1100-1112Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)35 Downloads (Pure) -
Optogenetic control of spine-head JNK reveals a role in dendritic spine regression
Hollós, P., John, J. M., Lehtonen, J. & Coffey, E., 2020, In: eNeuro. 7, 1, p. –Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile9 Citations (Scopus)19 Downloads (Pure) -
Probabilistic prediction of contacts in protein-ligand complexes
Hakulinen, R., Puranen, S., Lehtonen, J., Johnson, M. S. & Corander, 2012, In: PLoS ONE. 7, 11, p. –Research output: Contribution to journal › Article › Scientific › peer-review
3 Citations (Scopus)