Evaluation of Immunostimulatory Activities of Synthetic Mannose-Containing Structures Mimicking the beta-(1 -> 2)-Linked Cell Wall Mannans of Candida albicans

Kaarina Ranta; Kaisa Nieminen; Filip S. Ekholm; Moniká Poláková; Mattias U.Roslund [Unknown]; Tiina Saloranta; Reko Leino; Johannes Savolainen

doi:10.1128/CVI.00298-12

Evaluation of Immunostimulatory Activities of Synthetic Mannose-Containing Structures Mimicking the beta-(1 -> 2)-Linked Cell Wall Mannans of Candida albicans

Kaarina Ranta, Kaisa Nieminen, Filip S. Ekholm, Moniká Poláková, Mattias U.Roslund [Unknown], Tiina Saloranta, Reko Leino, Johannes Savolainen

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

24 Sitaatiot (Scopus)

Abstrakti

Immunostimulatory properties of synthetic structures mimicking the beta-(1 -> 2)-linked mannans of Candida albicans were evaluated in vitro. Contrary to earlier observations, tumor necrosis factor (TNF) production was not detected after stimulation with mannotetraose in mouse macrophages. Divalent disaccharide 1,4-bis(alpha-D-mannopyranosyloxy) butane induced TNF and some molecules induced low levels of gamma interferon (IFN-gamma) in human peripheral blood mononuclear cells (PBMC).

Alkuperäiskieli	Ei tiedossa
Sivut	1889–1893
Sivumäärä	5
Julkaisu	Clinical and Vaccine Immunology
Vuosikerta	19
Numero	11
DOI - pysyväislinkit	https://doi.org/10.1128/CVI.00298-12
Tila	Julkaistu - 2012
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Pääsy asiakirjaan

10.1128/CVI.00298-12

Viittausmuodot

Ranta, K., Nieminen, K., Ekholm, F. S., Poláková, M., [Unknown], M. U. R., Saloranta, T., Leino, R., & Savolainen, J. (2012). Evaluation of Immunostimulatory Activities of Synthetic Mannose-Containing Structures Mimicking the beta-(1 -> 2)-Linked Cell Wall Mannans of Candida albicans. Clinical and Vaccine Immunology, 19(11), 1889–1893. https://doi.org/10.1128/CVI.00298-12

@article{0ca7726dfd384b43b98c438757182924,

title = "Evaluation of Immunostimulatory Activities of Synthetic Mannose-Containing Structures Mimicking the beta-(1 -> 2)-Linked Cell Wall Mannans of Candida albicans",

abstract = "Immunostimulatory properties of synthetic structures mimicking the beta-(1 -> 2)-linked mannans of Candida albicans were evaluated in vitro. Contrary to earlier observations, tumor necrosis factor (TNF) production was not detected after stimulation with mannotetraose in mouse macrophages. Divalent disaccharide 1,4-bis(alpha-D-mannopyranosyloxy) butane induced TNF and some molecules induced low levels of gamma interferon (IFN-gamma) in human peripheral blood mononuclear cells (PBMC).",

author = "Kaarina Ranta and Kaisa Nieminen and Ekholm, {Filip S.} and Monik{\'a} Pol{\'a}kov{\'a} and [Unknown], {Mattias U.Roslund} and Tiina Saloranta and Reko Leino and Johannes Savolainen",

year = "2012",

doi = "10.1128/CVI.00298-12",

language = "Odefinierat/ok{\"a}nt",

volume = "19",

pages = "1889–1893",

journal = "Clinical and Vaccine Immunology",

issn = "1556-6811",

publisher = "American Society for Microbiology",

number = "11",

}

Ranta, K, Nieminen, K, Ekholm, FS, Poláková, M, [Unknown], MUR, Saloranta, T , Leino, R & Savolainen, J 2012, 'Evaluation of Immunostimulatory Activities of Synthetic Mannose-Containing Structures Mimicking the beta-(1 -> 2)-Linked Cell Wall Mannans of Candida albicans', Clinical and Vaccine Immunology, Vuosikerta 19, Nro 11, Sivut 1889–1893. https://doi.org/10.1128/CVI.00298-12

Evaluation of Immunostimulatory Activities of Synthetic Mannose-Containing Structures Mimicking the beta-(1 -> 2)-Linked Cell Wall Mannans of Candida albicans. / Ranta, Kaarina; Nieminen, Kaisa; Ekholm, Filip S. et al.
julkaisussa: Clinical and Vaccine Immunology, Vuosikerta 19, Nro 11, 2012, s. 1889–1893.

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Evaluation of Immunostimulatory Activities of Synthetic Mannose-Containing Structures Mimicking the beta-(1 -> 2)-Linked Cell Wall Mannans of Candida albicans

AU - Ranta, Kaarina

AU - Nieminen, Kaisa

AU - Ekholm, Filip S.

AU - Poláková, Moniká

AU - [Unknown], Mattias U.Roslund

AU - Saloranta, Tiina

AU - Leino, Reko

AU - Savolainen, Johannes

PY - 2012

Y1 - 2012

N2 - Immunostimulatory properties of synthetic structures mimicking the beta-(1 -> 2)-linked mannans of Candida albicans were evaluated in vitro. Contrary to earlier observations, tumor necrosis factor (TNF) production was not detected after stimulation with mannotetraose in mouse macrophages. Divalent disaccharide 1,4-bis(alpha-D-mannopyranosyloxy) butane induced TNF and some molecules induced low levels of gamma interferon (IFN-gamma) in human peripheral blood mononuclear cells (PBMC).

AB - Immunostimulatory properties of synthetic structures mimicking the beta-(1 -> 2)-linked mannans of Candida albicans were evaluated in vitro. Contrary to earlier observations, tumor necrosis factor (TNF) production was not detected after stimulation with mannotetraose in mouse macrophages. Divalent disaccharide 1,4-bis(alpha-D-mannopyranosyloxy) butane induced TNF and some molecules induced low levels of gamma interferon (IFN-gamma) in human peripheral blood mononuclear cells (PBMC).

U2 - 10.1128/CVI.00298-12

DO - 10.1128/CVI.00298-12

M3 - Artikel

SN - 1556-6811

VL - 19

SP - 1889

EP - 1893

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

IS - 11

ER -