@inproceedings{69383a28b9604a0fab94f64577179ab8,
title = "Enzymatic Boolean Logic Gates toward ON/OFF Sensing",
abstract = "In this paper we report a combined theoretical and experimental approach to develop enzyme logic gates networks (ELGN). ELGNs were tested in solution with optical analysis of the output signals. Then, the enzymes were immobilized on a buckypaper electrode for electrochemical transduction of the output signals. Finally, the switchable electrodes were integrated in a biofuel cell as a self-powered device for the detection of sucrose in adulterated wine samples.",
keywords = "biological cascade, Boolean logic gates, enzymes, modified electrodes, ON/OFF sensing",
author = "Paolo Bollella and Eleonora Macchia and Luisa Torsi",
note = "BOF 15/1 EK Funding Information: The following funding agencies are acknowledged: Academy of Finland projects #316881, #316883 {\textquoteleft}{\textquoteleft}Spatiotemporal control of Cell Functions{\textquoteright}{\textquoteright}, #332106 “ProSiT—Protein Detection at the Single-Molecule Limit with a Self-powered Organic Transistor for HIV early diagnosis”; Biosensori analitici usa-e getta a base di transistori organici auto-alimentati per la rivelazione di biomarcatori proteomici alla singola molecola per la diagnostica decentrata dell{\textquoteright}HIV (6CDD3786); Research for Innovation REFIN—Regione Puglia POR PUGLIA FESR-FSE 2014/2020; Dottorati innovativi con caratterizzazione industrial—PON R&I 2014–2020; “Sensore bio-elettronico usa-e-getta per l{\textquoteright}HIV autoalimentato da una cella a combustibile biologica” (BioElSens&Fuel); SiMBiT— Single molecule bio-electronic smart system array for clinical testing (Grant agreement ID: 824946); PMGB— Sviluppo di piattaforme meccatroniche, genomiche e bioinformatiche per l{\textquoteright}oncologia di precisione— ARS01_01195-PON “RICERCA E INNOVAZIONE” 2014–2020; {\AA}bo Akademi University CoE “Bioelectronic activation of cell functions”; and CSGI are acknowledged for partial financial support. Publisher Copyright: {\textcopyright} 2022 IEEE.; 2022 IEEE International Conference on Flexible and Printable Sensors and Systems, FLEPS 2022 ; Conference date: 10-07-2022 Through 13-07-2022",
year = "2022",
doi = "10.1109/FLEPS53764.2022.9781600",
language = "English",
booktitle = "FLEPS 2022 - IEEE International Conference on Flexible and Printable Sensors and Systems",
publisher = "the Institute of Electrical and Electronics Engineers, Inc.",
}