Abstract
A robust alcohol amination protocol using common saturated cyclic amines and primary alcohols as starting material is described for synthesis of 29 compounds. The reactions are catalyzed by combination of dichloro(p ‐cymene)ruthenium(II) dimer precatalyst with triphenylphosphine ligand. The catalyst can be precipitated by addition of hexane or cold diethyl ether, followed by isolation of the product as a hydrochloride salt without the need for chromatographic purification in most cases.
Original language | Undefined/Unknown |
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Pages (from-to) | 3030–3040 |
Journal | European Journal of Organic Chemistry |
Issue number | 20 |
DOIs | |
Publication status | Published - 2020 |
MoE publication type | A1 Journal article-refereed |