Indirect Lipid Transfer Protein Activity Measurements Using Quantification of Glycosphingolipid Production

Anders Backman; Josefin Halin; Matti Kjellberg; Peter Mattjus

doi:10.1007/978-1-4939-9136-5_9

Indirect Lipid Transfer Protein Activity Measurements Using Quantification of Glycosphingolipid Production

Anders Backman, Josefin Halin, Matti Kjellberg, Peter Mattjus

Solutions for Health

Research output: Chapter in Book/Conference proceeding › Chapter › Scientific › peer-review

5 Citations (Scopus)

Abstract

Here we summarize how glycosphingolipid production can be followed using metabolic labeling with radiolabeled lipid precursors. No assays are available yet that directly would address the lipid transfer protein activity in vivo. Therefore, these approaches can serve as tools to indirectly study the lipid transfer protein activity in cells, by monitoring their impact on the glycosphingolipid homeostasis.

Original language	Undefined/Unknown
Title of host publication	Intracellular Lipid Transport
Editors	Guillaume Drin
Publisher	Humana Press
Pages	105–114
ISBN (Electronic)	978-1-4939-9136-5
ISBN (Print)	978-1-4939-9135-8
DOIs	https://doi.org/10.1007/978-1-4939-9136-5_9
Publication status	Published - 2019
MoE publication type	A3 Part of a book or another research book

Keywords

LIPIDS
glycolipid transfer protein
lipid transfer

Access to Document

10.1007/978-1-4939-9136-5_9

https://link.springer.com/protocol/10.1007/978-1-4939-9136-5_9

Cite this

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title = "Indirect Lipid Transfer Protein Activity Measurements Using Quantification of Glycosphingolipid Production",

abstract = "Here we summarize how glycosphingolipid production can be followed using metabolic labeling with radiolabeled lipid precursors. No assays are available yet that directly would address the lipid transfer protein activity in vivo. Therefore, these approaches can serve as tools to indirectly study the lipid transfer protein activity in cells, by monitoring their impact on the glycosphingolipid homeostasis.",

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AU - Backman, Anders

AU - Halin, Josefin

AU - Kjellberg, Matti

AU - Mattjus, Peter

PY - 2019

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N2 - Here we summarize how glycosphingolipid production can be followed using metabolic labeling with radiolabeled lipid precursors. No assays are available yet that directly would address the lipid transfer protein activity in vivo. Therefore, these approaches can serve as tools to indirectly study the lipid transfer protein activity in cells, by monitoring their impact on the glycosphingolipid homeostasis.

AB - Here we summarize how glycosphingolipid production can be followed using metabolic labeling with radiolabeled lipid precursors. No assays are available yet that directly would address the lipid transfer protein activity in vivo. Therefore, these approaches can serve as tools to indirectly study the lipid transfer protein activity in cells, by monitoring their impact on the glycosphingolipid homeostasis.

KW - LIPIDS

KW - glycolipid transfer protein

KW - lipid transfer

KW - LIPIDS

KW - glycolipid transfer protein

KW - lipid transfer

KW - LIPIDS

KW - glycolipid transfer protein

KW - lipid transfer

U2 - 10.1007/978-1-4939-9136-5_9

DO - 10.1007/978-1-4939-9136-5_9

M3 - Kapitel

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