A novel antioxidant phenyl disaccharide from Populus tremula knotwood

Madalina Neacsu; Vicente Micol; Laura Pérez-Fons; Stefan Willför; Bjarne Holmbom; Ricardo Mallavia

doi:10.3390/12020205

A novel antioxidant phenyl disaccharide from Populus tremula knotwood

Madalina Neacsu^*, Vicente Micol, Laura Pérez-Fons, Stefan Willför, Bjarne Holmbom, Ricardo Mallavia

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

6 Citations (Scopus)

Abstract

The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 μM TE (Trolox Equivalents).

Original language	English
Pages (from-to)	205-217
Number of pages	13
Journal	Molecules
Volume	12
Issue number	2
DOIs	https://doi.org/10.3390/12020205
Publication status	Published - Feb 2007
MoE publication type	A1 Journal article-refereed

Keywords

Antioxidant
Coumaroyl glycoside
HPLC-MS/MS
Knotwood
NMR
p-coumaric acid
Phenyl disaccharide
Populus tremula

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title = "A novel antioxidant phenyl disaccharide from Populus tremula knotwood",

abstract = "The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 μM TE (Trolox Equivalents).",

keywords = "Antioxidant, Coumaroyl glycoside, HPLC-MS/MS, Knotwood, NMR, p-coumaric acid, Phenyl disaccharide, Populus tremula",

author = "Madalina Neacsu and Vicente Micol and Laura P{\'e}rez-Fons and Stefan Willf{\"o}r and Bjarne Holmbom and Ricardo Mallavia",

year = "2007",

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doi = "10.3390/12020205",

language = "English",

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pages = "205--217",

journal = "Molecules",

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T1 - A novel antioxidant phenyl disaccharide from Populus tremula knotwood

AU - Neacsu, Madalina

AU - Micol, Vicente

AU - Pérez-Fons, Laura

AU - Willför, Stefan

AU - Holmbom, Bjarne

AU - Mallavia, Ricardo

PY - 2007/2

Y1 - 2007/2

N2 - The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 μM TE (Trolox Equivalents).

AB - The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 μM TE (Trolox Equivalents).

KW - Antioxidant

KW - Coumaroyl glycoside

KW - HPLC-MS/MS

KW - Knotwood

KW - NMR

KW - p-coumaric acid

KW - Phenyl disaccharide

KW - Populus tremula

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U2 - 10.3390/12020205

DO - 10.3390/12020205

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VL - 12

SP - 205

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JO - Molecules

JF - Molecules

IS - 2

ER -

A novel antioxidant phenyl disaccharide from Populus tremula knotwood

Abstract

Keywords

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