A novel antioxidant phenyl disaccharide from Populus tremula knotwood

Madalina Neacsu*, Vicente Micol, Laura Pérez-Fons, Stefan Willför, Bjarne Holmbom, Ricardo Mallavia

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)


The complete characterization of two compounds obtained from the acetone extract of Populus tremula knotwood has been was achieved using LC-DAD-MS, MS/MS, IR and NMR. The new compounds were unequivocally identified as a mixture of the ester isomers of the (E) and (Z) p-coumarate of 1-O-rutinose. The isomers showed the capacity to inhibit lipid peroxidation induced by tert-butylhydroperoxide and to trap peroxyl radicals, as determined by a chemiluminescence method. These new phenyl disaccharides also showed a significant ORAC (oxygen radical absorbance capacity) value, i.e. 11.7 μM TE (Trolox Equivalents).

Original languageEnglish
Pages (from-to)205-217
Number of pages13
Issue number2
Publication statusPublished - Feb 2007
MoE publication typeA1 Journal article-refereed


  • Antioxidant
  • Coumaroyl glycoside
  • Knotwood
  • NMR
  • p-coumaric acid
  • Phenyl disaccharide
  • Populus tremula


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