TY - JOUR
T1 - Impact of solution pH (5–9) and dissolution products on in vitro behaviour of the bioactive glass S53P4
AU - Siekkinen, Minna
AU - Engblom, Markus
AU - Hupa, Leena
N1 - Publisher Copyright:
© 2023
PY - 2023/12
Y1 - 2023/12
N2 - The impact of dissolution products on the reaction behaviour of bioactive glasses was explored. Bioactive glass S53P4 particles were immersed in solutions with initial pH of 5–9. After 24 and 72 h, the solution extracts were used for testing unreacted particles. The pH, ion concentrations, and glass surfaces were analysed as functions of immersion time. More Ca, Na, and P dissolved at lower pH (5) than at higher pH (7.4 or 9). The dissolution changed from an incongruent to an apparent congruent with increasing pH. Dissolution products in extracts changed the reaction layer structure on glass particles and led to lower ion release at pH 7.4 and 9. Dissolution increased almost linearly with time in acidic solutions. Silica-rich layer and calcium phosphate were identified on the particles after immersion in all solutions except at pH 9. Local ion concentration variations affected dissolution, leading to nonuniform ion release rates.
AB - The impact of dissolution products on the reaction behaviour of bioactive glasses was explored. Bioactive glass S53P4 particles were immersed in solutions with initial pH of 5–9. After 24 and 72 h, the solution extracts were used for testing unreacted particles. The pH, ion concentrations, and glass surfaces were analysed as functions of immersion time. More Ca, Na, and P dissolved at lower pH (5) than at higher pH (7.4 or 9). The dissolution changed from an incongruent to an apparent congruent with increasing pH. Dissolution products in extracts changed the reaction layer structure on glass particles and led to lower ion release at pH 7.4 and 9. Dissolution increased almost linearly with time in acidic solutions. Silica-rich layer and calcium phosphate were identified on the particles after immersion in all solutions except at pH 9. Local ion concentration variations affected dissolution, leading to nonuniform ion release rates.
KW - Bioactive glass
KW - Buffer solutions
KW - Dissolution kinetics
KW - In vitro
UR - http://www.scopus.com/inward/record.url?scp=85170409532&partnerID=8YFLogxK
U2 - 10.1016/j.nocx.2023.100199
DO - 10.1016/j.nocx.2023.100199
M3 - Article
AN - SCOPUS:85170409532
SN - 2590-1591
VL - 20
JO - Journal of Non-Crystalline Solids: X
JF - Journal of Non-Crystalline Solids: X
M1 - 100199
ER -