First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment (Finland)

Lisa Spoof; Katri A. Berg; Jarkko Rapala; Kirsti Lahti; Liisa Lepistö; James S. Metcalf; Geoffrey A. Codd; Jussi Meriluoto

doi:10.1002/tox.20216

First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment (Finland)

Lisa Spoof, Katri A. Berg, Jarkko Rapala, Kirsti Lahti, Liisa Lepistö, James S. Metcalf, Geoffrey A. Codd, Jussi Meriluoto^*

^*Corresponding author for this work

Laboratoryservices

Research output: Contribution to journal › Article › Scientific › peer-review

144 Citations (Scopus)

Abstract

The cyanobacterial cytotoxin cylindrospermopsin has been mostly associated with cyanobacteria present in tropical and subtropical regions. Cylindrospermopsin has recently been found in cyanobacterial samples in central and southern Europe but the possible presence of the toxin in northern Europe has been unknown. Fifty-eight field and laboratory culture samples of Finnish cyanobacteria were analyzed by high-performance liquid chromatography combined with UV diode-array detection, multiple reactant monitoring in a triple-quadrupole mass spectrometer (MS), and accurate mass measurements using a time-of-flight MS instrument. Cylindrospermopsin was confirmed by all three techniques in a culture sample of Anabaena lapponica at a concentration of 242 μg cylindrospermopsin per g freeze-dried cyanobacterial material.

Original language	English
Pages (from-to)	552-560
Number of pages	9
Journal	Environmental Toxicology
Volume	21
Issue number	6
DOIs	https://doi.org/10.1002/tox.20216
Publication status	Published - 2006
MoE publication type	A1 Journal article-refereed

Keywords

Anabaena lapponica
Cyanobacteria
Cylindrospermopsin
Liquid chromatography
Mass spectrometry

Access to Document

10.1002/tox.20216

Cite this

@article{c2eabac9a9fb4226b76bd1a321d47f05,

title = "First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment (Finland)",

abstract = "The cyanobacterial cytotoxin cylindrospermopsin has been mostly associated with cyanobacteria present in tropical and subtropical regions. Cylindrospermopsin has recently been found in cyanobacterial samples in central and southern Europe but the possible presence of the toxin in northern Europe has been unknown. Fifty-eight field and laboratory culture samples of Finnish cyanobacteria were analyzed by high-performance liquid chromatography combined with UV diode-array detection, multiple reactant monitoring in a triple-quadrupole mass spectrometer (MS), and accurate mass measurements using a time-of-flight MS instrument. Cylindrospermopsin was confirmed by all three techniques in a culture sample of Anabaena lapponica at a concentration of 242 μg cylindrospermopsin per g freeze-dried cyanobacterial material.",

keywords = "Anabaena lapponica, Cyanobacteria, Cylindrospermopsin, Liquid chromatography, Mass spectrometry",

author = "Lisa Spoof and Berg, {Katri A.} and Jarkko Rapala and Kirsti Lahti and Liisa Lepist{\"o} and Metcalf, {James S.} and Codd, {Geoffrey A.} and Jussi Meriluoto",

year = "2006",

doi = "10.1002/tox.20216",

language = "English",

volume = "21",

pages = "552--560",

journal = "Environmental Toxicology",

issn = "1520-4081",

publisher = "Wiley",

number = "6",

}

TY - JOUR

T1 - First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment (Finland)

AU - Spoof, Lisa

AU - Berg, Katri A.

AU - Rapala, Jarkko

AU - Lahti, Kirsti

AU - Lepistö, Liisa

AU - Metcalf, James S.

AU - Codd, Geoffrey A.

AU - Meriluoto, Jussi

PY - 2006

Y1 - 2006

N2 - The cyanobacterial cytotoxin cylindrospermopsin has been mostly associated with cyanobacteria present in tropical and subtropical regions. Cylindrospermopsin has recently been found in cyanobacterial samples in central and southern Europe but the possible presence of the toxin in northern Europe has been unknown. Fifty-eight field and laboratory culture samples of Finnish cyanobacteria were analyzed by high-performance liquid chromatography combined with UV diode-array detection, multiple reactant monitoring in a triple-quadrupole mass spectrometer (MS), and accurate mass measurements using a time-of-flight MS instrument. Cylindrospermopsin was confirmed by all three techniques in a culture sample of Anabaena lapponica at a concentration of 242 μg cylindrospermopsin per g freeze-dried cyanobacterial material.

AB - The cyanobacterial cytotoxin cylindrospermopsin has been mostly associated with cyanobacteria present in tropical and subtropical regions. Cylindrospermopsin has recently been found in cyanobacterial samples in central and southern Europe but the possible presence of the toxin in northern Europe has been unknown. Fifty-eight field and laboratory culture samples of Finnish cyanobacteria were analyzed by high-performance liquid chromatography combined with UV diode-array detection, multiple reactant monitoring in a triple-quadrupole mass spectrometer (MS), and accurate mass measurements using a time-of-flight MS instrument. Cylindrospermopsin was confirmed by all three techniques in a culture sample of Anabaena lapponica at a concentration of 242 μg cylindrospermopsin per g freeze-dried cyanobacterial material.

KW - Anabaena lapponica

KW - Cyanobacteria

KW - Cylindrospermopsin

KW - Liquid chromatography

KW - Mass spectrometry

UR - http://www.scopus.com/inward/record.url?scp=33751250223&partnerID=8YFLogxK

U2 - 10.1002/tox.20216

DO - 10.1002/tox.20216

M3 - Article

C2 - 17091499

AN - SCOPUS:33751250223

SN - 1520-4081

VL - 21

SP - 552

EP - 560

JO - Environmental Toxicology

JF - Environmental Toxicology

IS - 6

ER -

First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment (Finland)

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this