Catalytic activity of hierarchical beta zeolites in the Prins cyclization of (−)-isopulegol with acetone

Mathias Laluc, Roman Barakov, Päivi Mäki-Arvela, Nataliya Shcherban, Dmitry Yu Murzin*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Several hierarchical beta zeolites prepared via hydrothermal treatment of a concentrated zeolite gel-precursor were investigated in Prins cyclisation between (–)-isopulegol and acetone acting as a reactant and a solvent for production of a chromenol compound exhibiting antiviral activity. The catalysts were characterized by SEM, TEM, nitrogen physisorption, ammonia TPD, adsorption-desorption of pyridine and 2,4,6-tri-tert-butylpyridine with FTIR spectroscopy. For the Prins cyclization performed at 30 °C, the highest yield of the desired product was obtained over a zeolite catalyst containing a developed mesoporosity with a uniform mesopore size and an optimum ratio of Brønsted to Lewis acid sites.

Original languageEnglish
Article number118131
JournalApplied Catalysis A: General
Volume618
DOIs
Publication statusPublished - 25 May 2021
MoE publication typeA1 Journal article-refereed

Keywords

  • Chromenol
  • Hierarchical zeolite
  • Prins cyclisation
  • Tetrahydropyran ring structure

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