Bioactivity and dissolution behavior of boron-containing bioactive glasses under static and dynamic conditions in different media

Marcela Arango-Ospina, Leena Hupa, Aldo R. Boccaccini

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    The present study reports the dissolution studies of a family of boron-doped bioactive glasses based on the composition ICIE16. Simulated body fluid (SBF), Tris-buffered solution and lactic acid were used as dissolution media for studies under static and dynamic conditions. The leaching of ions from the glasses under the evaluated conditions and media was compared and the bioactive behaviour of the glasses was evaluated. Influence of the incorporation of boron in the thermal properties of the glass was also analysed. Glasses exhibited faster bioactivity under dynamic dissolution configuration compared to static conditions. Moreover, the glass dissolution rate was faster in acidic conditions than in SBF or Tris solutions. It was found that at increasing boron content the dissolution of the glass is faster.

    Original languageUndefined/Unknown
    Pages (from-to)124–139
    JournalBiomedical Glasses
    Issue number1
    Publication statusPublished - 2019
    MoE publication typeA1 Journal article-refereed

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