OBJECTIVE: The objective of the study was to investigate the associations of sedentary time, physical activity, and cardiorespiratory fitness with skeletal muscle glucose uptake (GU).
METHODS: Sedentary time and physical activity were measured with accelerometers and VO2 max with cycle ergometry in 44 sedentary adults with metabolic syndrome. Thigh muscle GU was determined with [18 F]FDG-PET imaging.
RESULTS: Sedentary time (β = -0.374), standing (β = 0.376), steps (β = 0.351), and VO2 max (β = 0.598) were associated with muscle GU when adjusted for sex, age, and accelerometer wear time. Adjustment for body fat-% turned all associations non-significant.
CONCLUSION: Body composition is a more important determinant of muscle GU in this population than sedentary time, physical activity, or fitness.
|Number of pages||6|
|Journal||Scandinavian Journal of Medicine and Science in Sports|
|Publication status||E-pub ahead of print - 14 Dec 2022|
|MoE publication type||A1 Journal article-refereed|