Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species

Izabela Redzynia, Natasza E. Ziólkowska, Wieslaw R. Majzner, Stefan Willför, Rainer Sjöholm, Patrik Christoffer Eklund, Grzegorz Bujacz

    Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

    10 Citeringar (Scopus)

    Sammanfattning

    X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol crystal. The investigated compounds inhibit lipid peroxidation and lariciresinol is additionally a good scavenger of superoxide radicals. The structural data presented in this work provide a useful basis for designing more active compounds with potential use as antioxidants.
    OriginalspråkOdefinierat/okänt
    Sidor (från-till)4147–4158
    Antal sidor12
    TidskriftMolecules
    Volym14
    Utgåva10
    DOI
    StatusPublicerad - 2009
    MoE-publikationstypA1 Tidskriftsartikel-refererad

    Nyckelord

    • "host - guest" inclusion crystals
    • antioxidant potency
    • crystal structure
    • flavonoids
    • lignans
    • phenolic compounds

    Citera det här