Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems

V Mishra, Kuldeep Bansal, A Verma, N Yadav, S Thakur, K Sudhakar, Jessica Rosenholm

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

469 Citeringar (Scopus)
364 Nedladdningar (Pure)

Sammanfattning

Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications.
OriginalspråkOdefinierat/okänt
Sidor (från-till)
TidskriftPharmaceutics
Volym10
Nummer4
DOI
StatusPublicerad - 2018
MoE-publikationstypA1 Tidskriftsartikel-refererad

Nyckelord

  • drug delivery
  • drug-delivery systems
  • Colloidal nanoparticles
  • cytotoxicity
  • solid lipid
  • Nanoparticles

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