SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.

Peuhu, Kaukonen, Lerche, Saari, Guzmán, Rantakari, De Franceschi, Wärri, Georgiadou, Guillaume Jacquemet, Mattila, Virtakoivu, Liu, Attieh, Silva, Betz, Sundberg, Salmi, Deugnier, EliceiriIvaska

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

32 Citeringar (Scopus)

Sammanfattning

mammary gland stromal fibroblasts demonstrated defects in collagen fibre assembly, collagen contraction and degradation in vitro Together, these data imply that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic manner by controlling the organisation of the stromal ECM.
OriginalspråkOdefinierat/okänt
Sidor (från-till)165–182
TidskriftEMBO Journal
Volym36
Nummer2
DOI
StatusPublicerad - 2017
MoE-publikationstypA1 Tidskriftsartikel-refererad

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