Rhamnosylation of lignans by a Streptomyces strain

Patrik Christoffer Eklund; Toni Holmström; Lamis Al-Ubaydy; Rainer Sjöholm; Juha Hakala

doi:10.1016/j.tetlet.2005.12.107

Rhamnosylation of lignans by a Streptomyces strain

Patrik Christoffer Eklund, Toni Holmström, Lamis Al-Ubaydy, Rainer Sjöholm, Juha Hakala

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

6 Citeringar (Scopus)

Sammanfattning

Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.

Originalspråk	Odefinierat/okänt
Sidor (från-till)	1645–1648
Antal sidor	4
Tidskrift	Tetrahedron Letters
Volym	47
Nummer	10
DOI	https://doi.org/10.1016/j.tetlet.2005.12.107
Status	Publicerad - 2006
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

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10.1016/j.tetlet.2005.12.107

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abstract = "Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.",

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AU - Holmström, Toni

AU - Al-Ubaydy, Lamis

AU - Sjöholm, Rainer

AU - Hakala, Juha

PY - 2006

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AB - Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.

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