Providing cellular signposts--post-translational modifications of intermediate filaments

Claire Hyder, Pallari, Vitaly Kochin, John Eriksson

    Forskningsoutput: TidskriftsbidragÖversiktsartikelPeer review

    61 Citeringar (Scopus)

    Sammanfattning

    Intermediate filaments are dynamically regulated by their post-translational modifications. Initially these modifications were found to regulate filament dynamics and organization. In the last few years, their roles have extended significantly to facilitating, for example, the recruitment and sequestration of signaling molecules that regulate a wide range of cellular functions. While phosphorylation has been established as the principal post-translational modification regulating intermediate filament function, other modifications with co-operative roles are emerging, adding a further dimensions to intermediate filament-mediated signaling.
    OriginalspråkOdefinierat/okänt
    Sidor (från-till)2140–2148
    TidskriftFEBS Letters
    Volym582
    Utgåva14
    DOI
    StatusPublicerad - 2008
    MoE-publikationstypA2 Granska artikel i en vetenskaplig tidskrift

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