Optical imaging of fluorescent carbon biomarkers using artificial neural networks

Tatiana A. Dolenko, Sergey A. Burikov, Alexey M. Vervald, Igor I. Vlasov, Sergey A. Dolenko, Kirill A. Laptinskiy, Jessica Rosenholm, Olga A. Shenderova

    Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

    13 Citeringar (Scopus)

    Sammanfattning

    The principle possibility of extraction of fluorescence of nanoparticles in the presence of background autofluorescence of a biological environment using neural network algorithms is demonstrated. It is shown that the methods used allow detection of carbon nanoparticles fluorescence against the background of the autofluorescence of egg white with a sufficiently low concentration detection threshold (not more than 2 μg∕ml for carbon dots and 3 μg∕ml for nanodiamonds). It was also shown that the use of the input data compression can further improve the accuracy of solving the inverse problem by 1.5 times.
    OriginalspråkOdefinierat/okänt
    Sidor (från-till)
    TidskriftJournal of Biomedical Optics
    Volym19
    Utgåva11
    DOI
    StatusPublicerad - 2014
    MoE-publikationstypA1 Tidskriftsartikel-refererad

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