Hot gas desulfurization with regenerable metal oxide sorbents is an essential part of the simplified integrated gasification combined cycle process which is currently being demonstrated at commercial scale. As part of a sulfur removal process development, Carbona Corporation is developing fluidized-bed reactor models for scale-up. In the first part of this work, the parameters for an uniform conversion model were determined to describe the conversion rate of ZnS regeneration with oxygen. A method using the uniform conversion model for fluidized-bed application is presented in this paper. The apparent activation energy for the global reaction rate constant obtained from pilot-scale fluidized-bed tests is 200-210 kJ/mol. When using these reaction rate constants as inputs of a sensitivity analysis for a large-scale reactor model, in comparison with the rate constants reported earlier, some differences can be observed. The significance of the differences are discussed. It is stated that any zinc sulfate formed in fluidized-bed regeneration at temperatures 500-600°C will decompose, forming SO2, at the actual regeneration temperatures of the bed (725-800°C) due to neglible O2 partial pressure.