Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings

Katriina Kurki-Helasmo; Jussi Meriluoto

doi:10.1016/S0041-0101(98)00114-7

Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings

Katriina Kurki-Helasmo
, Jussi Meriluoto^*

^*Korresponderande författare för detta arbete

Laboratoryservices

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

89 Citeringar (Scopus)

Sammanfattning

Mustard (Sinapis alba L.) seeds were cultivated for seven days on a solid nutrient medium supplemented with 0-40μg microcystin-RR per ml. Microcystin-RR affected seedling growth (ic₅₀ 0.8μg/ml) and microcystin concentrations ≥5.0μg/ml produced malformed plants. The inhibition of protein phosphatase 1 and 2A activity correlated with the growth inhibition. The seedlings were also shown to take up ³H-dihydromicrocystin-LR derived radioactivity up to a level corresponding to ca. 80ng toxin per mg plant protein. Copyright (C) 1998 Elsevier Science Ltd.

Originalspråk	Engelska
Sidor (från-till)	1921-1926
Antal sidor	6
Tidskrift	Toxicon
Volym	36
Nummer	12
DOI	https://doi.org/10.1016/S0041-0101(98)00114-7
Status	Publicerad - dec. 1998
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Finansiering

We thank Maj and Tor Nessling Foundation for financial support, Dr. Diana Toivola, Åbo Akademi University, for help with the toxin uptake studies and Dr. Eva-Mari Aro, Dr. Eevi Rintamäki and Dr. Juhani Lehtonen, University of Turku, for helpful discussions.

Åtkomst av dokument

10.1016/S0041-0101(98)00114-7

Andra filer och länkar

Länk till publikationen i Scopus

Citera det här

@article{6a2811a03dcb4f66a8fed1bb7835f984,

title = "Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings",

abstract = "Mustard (Sinapis alba L.) seeds were cultivated for seven days on a solid nutrient medium supplemented with 0-40μg microcystin-RR per ml. Microcystin-RR affected seedling growth (ic50 0.8μg/ml) and microcystin concentrations ≥5.0μg/ml produced malformed plants. The inhibition of protein phosphatase 1 and 2A activity correlated with the growth inhibition. The seedlings were also shown to take up 3H-dihydromicrocystin-LR derived radioactivity up to a level corresponding to ca. 80ng toxin per mg plant protein. Copyright (C) 1998 Elsevier Science Ltd.",

author = "Katriina Kurki-Helasmo and Jussi Meriluoto",

note = "Funding Information: We thank Maj and Tor Nessling Foundation for financial support, Dr. Diana Toivola, {\AA}bo Akademi University, for help with the toxin uptake studies and Dr. Eva-Mari Aro, Dr. Eevi Rintam{\"a}ki and Dr. Juhani Lehtonen, University of Turku, for helpful discussions. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.",

year = "1998",

month = dec,

doi = "10.1016/S0041-0101(98)00114-7",

language = "English",

volume = "36",

pages = "1921--1926",

journal = "Toxicon",

issn = "0041-0101",

publisher = "Elsevier",

number = "12",

}

TY - JOUR

T1 - Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings

AU - Kurki-Helasmo, Katriina

AU - Meriluoto, Jussi

N1 - Funding Information: We thank Maj and Tor Nessling Foundation for financial support, Dr. Diana Toivola, Åbo Akademi University, for help with the toxin uptake studies and Dr. Eva-Mari Aro, Dr. Eevi Rintamäki and Dr. Juhani Lehtonen, University of Turku, for helpful discussions. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.

PY - 1998/12

Y1 - 1998/12

N2 - Mustard (Sinapis alba L.) seeds were cultivated for seven days on a solid nutrient medium supplemented with 0-40μg microcystin-RR per ml. Microcystin-RR affected seedling growth (ic50 0.8μg/ml) and microcystin concentrations ≥5.0μg/ml produced malformed plants. The inhibition of protein phosphatase 1 and 2A activity correlated with the growth inhibition. The seedlings were also shown to take up 3H-dihydromicrocystin-LR derived radioactivity up to a level corresponding to ca. 80ng toxin per mg plant protein. Copyright (C) 1998 Elsevier Science Ltd.

AB - Mustard (Sinapis alba L.) seeds were cultivated for seven days on a solid nutrient medium supplemented with 0-40μg microcystin-RR per ml. Microcystin-RR affected seedling growth (ic50 0.8μg/ml) and microcystin concentrations ≥5.0μg/ml produced malformed plants. The inhibition of protein phosphatase 1 and 2A activity correlated with the growth inhibition. The seedlings were also shown to take up 3H-dihydromicrocystin-LR derived radioactivity up to a level corresponding to ca. 80ng toxin per mg plant protein. Copyright (C) 1998 Elsevier Science Ltd.

UR - https://www.scopus.com/pages/publications/0032400792

U2 - 10.1016/S0041-0101(98)00114-7

DO - 10.1016/S0041-0101(98)00114-7

M3 - Article

C2 - 9839676

AN - SCOPUS:0032400792

SN - 0041-0101

VL - 36

SP - 1921

EP - 1926

JO - Toxicon

JF - Toxicon

IS - 12

ER -

Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings

Sammanfattning

Finansiering

Åtkomst av dokument

Andra filer och länkar

Fingeravtryck

Citera det här