Mesoporous Silica Nanoparticles as Carriers for Biomolecules in Cancer Therapy

Berrin Küçüktürkmen, Jessica M. Rosenholm

Forskningsoutput: Kapitel i bok/konferenshandlingKapitelVetenskapligPeer review

6 Nedladdningar (Pure)

Sammanfattning

Mesoporous silica nanoparticles (MSNs) offer many advantageous properties for applications in the field of nanobiotechnology. Loading of small molecules into MSNs is straightforward and widely applied, but with the upswing of both research and commercial interest in biological drugs in recent years, also biomacromolecules have been loaded into MSNs for delivery purposes. MSNs possess many critical properties making them a promising and versatile carrier for biomacromolecular delivery. In this chapter, we review the effects of the various structural parameters of MSNs on the effective loading of biomacromolecular therapeutics, with focus on maintaining stability and drug delivery performance. We also emphasize recent studies involving the use of MSNs in the delivery of biomacromolecular drugs, especially for cancer treatment.
OriginalspråkEngelska
Titel på gästpublikationBio-Nanomedicine for Cancer Therapy
RedaktörerFlavia Fontana, Hélder A. Santos
UtgivningsortCham
FörlagSpringer International Publishing
Sidor99-120
ISBN (elektroniskt)978-3-030-58174-9
ISBN (tryckt)978-3-030-58173-2
DOI
StatusPublicerad - 2 feb 2021
MoE-publikationstypA3 Del av bok eller annan forskningsbok

Publikationsserier

NamnAdvances in Experimental Medicine and Biology
Volym1295
ISSN (tryckt)0065-2598
ISSN (elektroniskt)2214-8019

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