Intermediate filament dynamics

John Eriksson, P Opal, RD Goldman

    Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

    125 Citeringar (Scopus)

    Sammanfattning

    The view of intermediate filaments as static cytoskeletal elements is changing. Studies of exogenous intermediate filament proteins, either microinjected or expressed from transfected genes, have demonstrated that a continuous incorporation of subunits into the polymerized filaments is taking place. This incorporation appears to be required for maintaining normal cytoplasmic networks of intermediate filaments. At the post-translational level, phosphorylation is an important factor in regulating dynamic aspects of intermediate filament organization and structure.
    OriginalspråkOdefinierat/okänt
    Sidor (från-till)99–104
    TidskriftCurrent Opinion in Cell Biology
    Volym4
    Utgåva1
    StatusPublicerad - 1992
    MoE-publikationstypA2 Granska artikel i en vetenskaplig tidskrift

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