TY - GEN
T1 - Flexible Carbon-based electrodes for amperometric biosensor development
AU - Tricase, Angelo
AU - Marchiano, Verdiana
AU - Macchia, Eleonora
AU - Kidayaveettil, Reshma
AU - Leech, Donal
AU - Scamarcio, Gaetano
AU - Perchiazzi, Gaetano
AU - Torsi, Luisa
AU - Bollella, Paolo
N1 - Publisher Copyright:
© 2024 IEEE.
PY - 2024
Y1 - 2024
N2 - This study presents the development of second-generation wearable biosensor arrays using printed electrode technology with a homemade water-based graphite ink. The electrodes were prepared by stencil-printing, then modified with [Os(bpy)2(Cl)(PVI)10] to facilitate electron transfer from lactate oxidase (LOx) and glucose oxidase (GOx). These biosensor arrays exhibit a low limit of detection, high sensitivities, and selectivity when tested in both buffer solution and artificial sweat. They also demonstrate good operational/storage stability, retaining about 80% of the initial signal after 20 days. Integrated into a wristband, the biosensors were successfully tested for continuous monitoring of L-lactate and D-glucose in a healthy volunteer during daily activities. This technology holds potential for real-time wearable applications in different fields, ranging from sports to medicine and healthcare.
AB - This study presents the development of second-generation wearable biosensor arrays using printed electrode technology with a homemade water-based graphite ink. The electrodes were prepared by stencil-printing, then modified with [Os(bpy)2(Cl)(PVI)10] to facilitate electron transfer from lactate oxidase (LOx) and glucose oxidase (GOx). These biosensor arrays exhibit a low limit of detection, high sensitivities, and selectivity when tested in both buffer solution and artificial sweat. They also demonstrate good operational/storage stability, retaining about 80% of the initial signal after 20 days. Integrated into a wristband, the biosensors were successfully tested for continuous monitoring of L-lactate and D-glucose in a healthy volunteer during daily activities. This technology holds potential for real-time wearable applications in different fields, ranging from sports to medicine and healthcare.
KW - enzymatic biosensor
KW - Stencil printing electrodes
KW - wearable electrodes
UR - https://www.scopus.com/pages/publications/85200772753
U2 - 10.1109/FLEPS61194.2024.10603574
DO - 10.1109/FLEPS61194.2024.10603574
M3 - Published conference proceeding
AN - SCOPUS:85200772753
T3 - FLEPS 2024 - IEEE International Conference on Flexible and Printable Sensors and Systems, Proceedings
BT - 2024 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS)
PB - the Institute of Electrical and Electronics Engineers, Inc.
T2 - 6th IEEE International Conference on Flexible and Printable Sensors and Systems, FLEPS 2024
Y2 - 30 June 2024 through 3 July 2024
ER -