Sammanfattning
Copper-mediated radiofluorination is a straightforward method to produce a variety of [18F]fluoroarenes and [18F]fluoroheteroarenes. To minimize the number of steps in the production of 18F-labelled radiopharmaceuticals, we have developed a short and efficient azeotropic drying-free 18F-labelling method using copper-mediated fluorination. Our goal was to improve the copper-mediated method to achieve wide substrate scope with good radiochemical yields with short synthesis time.
Originalspråk | Odefinierat/okänt |
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Sidor (från-till) | – |
Tidskrift | EJNMMI Radiopharmacy and Chemistry |
Volym | 4 |
DOI | |
Status | Publicerad - 2019 |
MoE-publikationstyp | A1 Tidskriftsartikel-refererad |