Enzyme based field effect transistor: State-of-the-art and future perspectives

Lucia Sarcina; Eleonora Macchia; Angelo Tricase; Cecilia Scandurra; Anna Imbriano; Fabrizio Torricelli; Nicola Cioffi; Luisa Torsi; Paolo Bollella

doi:10.1002/elsa.202100216

Enzyme based field effect transistor: State-of-the-art and future perspectives

Lucia Sarcina
, Eleonora Macchia
, Angelo Tricase
, Cecilia Scandurra
, Anna Imbriano
, Fabrizio Torricelli
, Nicola Cioffi
, Luisa Torsi^*
, Paolo Bollella^*

^*Korresponderande författare för detta arbete

Fysik

Forskningsoutput: Tidskriftsbidrag › Kort undersökning › Peer review

24 Citeringar (Scopus)

85 Nedladdningar (Pure)

Sammanfattning

The review discloses the historical and technological evolution of enzyme-based field-effect transistors (EnFETs) underlying the importance of gate electrode modification toward the implementation of novel FETs configurations such as extended-gate FET (EG-FETs) or EG organic FETs (EG-OFETs). The working principle of the EnFETs as postulated by Bergveld in 1970, who defined the EnFET as an ion-selective FET (ISFET) modified with enzyme-membrane, is also discussed considering the analytical equations related to the EnFET output response. For each category, namely EnFETs, EG-FETs, and EG-OFETs, we reviewed the key devices’ configurations that addressed the research in this field in the last 40 years with particular attention to the analytical figures of merit.

Originalspråk	Engelska
Artikelnummer	e2100216
Tidskrift	Electrochemical Science Advances
Volym	3
Nummer	3
DOI	https://doi.org/10.1002/elsa.202100216
Status	Publicerad - juni 2023
MoE-publikationstyp	O2 Other

Finansiering

Lucia Sarcina and Eleonora Macchia contributed equally to this work. The following funding agencies are acknowledged: Academy of Finland projects #316881, #316883 ‘‘Spatiotemporal control of Cell Functions’’, #332106 “ProSiT—Protein Detection at the Single‐Molecule Limit with a Self‐powered Organic Transistor for HIV early diagnosis”; Biosensori analitici usa‐e getta a base di transistori organici auto‐alimentati per la rivelazione di biomarcatori proteomici alla singola molecola per la diagnostica decentrata dell'HIV (6CDD3786); Research for Innovation REFIN—Regione Puglia POR PUGLIA FESR‐FSE 2014/2020; Dottorati innovativi con caratterizzazione industrial—PON R&I 2014–2020; “Sensore bio‐elettronico usa‐e‐getta per l'HIV autoalimentato da una cella a combustibile biologica” (BioElSens&Fuel); SiMBiT—Single molecule bio‐electronic smart system array for clinical testing (Grant agreement ID: 824946); PMGB—Sviluppo di piattaforme meccatroniche, genomiche e bioinformatiche per l'oncologia di precisione—ARS01_01195‐PON “RICERCA E INNOVAZIONE” 2014–2020; Åbo Akademi University CoE “Bioelectronic activation of cell functions”; and CSGI are acknowledged for partial financial support.

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10.1002/elsa.202100216Licens: CC BY

Electrochemical Science Adv - 2022 - Sarcina - Enzyme based field effect transistor State‐of‐the‐art and futureSlutlig publicerad version, 2,22 MBLicens: CC BY

https://urn.fi/URN:NBN:fi-fe202401314929

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AU - Cioffi, Nicola

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Enzyme based field effect transistor: State-of-the-art and future perspectives

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