Electronic biosensors based on EGOFETs

Mohammad Y. Mulla, Luisa Torsi, Kyriaki Manoli

Forskningsoutput: Kapitel i bok/konferenshandlingKapitelVetenskapligPeer review

Sammanfattning

There is an increasing interest for low cost, ultrasensitive, time saving yet reliable, point-of-care bioelectronic sensors. Electrolyte gated organic field effect transistors (EGOFETs) are proven compelling transducers for various sensing applications, offering direct electronic, label-free transduction of bio-recognition events along with miniaturization, fast data handling and processing. Given that field effect transistors act as intrinsically signal amplifiers, even a small change of a chemical or biological quantity may significantly alter the output electronic signal. In EGOFETs selectivity can be guaranteed by the immobilization of bioreceptors able to bind specifically a target analyte. The layer of receptors can be linked to one of the electronic active interfaces of the transistor, and the interactions with a target molecule affect the electronic properties of the device. The present chapter discusses main aspects of EGOFETs transducers along with detailed examples of how to tailor the device interfaces with desired functionality. The development of an “electronic tongue” based on an EGOFET device coupled to odorant binding proteins (OBPs) for enantiomers differentiation is presented.
OriginalspråkEngelska
Titel på gästpublikationOdorant Binding and Chemosensory Proteins
RedaktörerPaolo Pelosi, Wolfgang Knoll
FörlagElsevier
Kapitel17
Sidor403-433
Antal sidor31
Volym642
ISBN (tryckt)978-0-12-821157-1
DOI
StatusPublicerad - 2020
MoE-publikationstypA3 Del av bok eller annan forskningsbok

Publikationsserier

NamnMethods in Enzymology
FörlagElsevier
ISSN (tryckt)0076-6879

Fingeravtryck Fördjupa i forskningsämnen för ”Electronic biosensors based on EGOFETs”. Tillsammans bildar de ett unikt fingeravtryck.

Citera det här