Dicarbonylchloro(pentabenzylcyclopentadienyl)ruthenium as Racemization Catalyst in the Dynamic Kinetic Resolution of Secondary Alcohols

D Mavrynsky, M Paivio, K Lundell, R Sillanpaa, LT Kanerva, Reko Leino

    Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

    29 Citeringar (Scopus)

    Sammanfattning

    Dicarbonylchloro(pentabenzylcyclopentadienyl)ruthenium has been prepared and its structure confirmed by X-ray analysis, This complex shows excellent catalytic activity and modest stability against air in racemization reactions of secondary alcohols. In Candida antarctica lipase B (CAL-B) catalyzed dynamic kinetic resolution (DKR) of 1-phenyl- and 1-(furan-2-yl)ethanol compounds, the new complex shows improved performance as an alcohol racemization catalyst in comparison with its well-known pentaphenylcyclopentadienyl analogue, hitherto considered as the leading catalyst candidate. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
    OriginalspråkOdefinierat/okänt
    Sidor (från-till)1317–1320
    Antal sidor4
    TidskriftEuropean Journal of Organic Chemistry
    Volym2009
    Utgåva9
    DOI
    StatusPublicerad - 2009
    MoE-publikationstypA1 Tidskriftsartikel-refererad

    Nyckelord

    • Cyclopentadienyl ligands
    • Dynamic kinetic resolution
    • Enzyme catalysis
    • Racemization
    • Ruthenium

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