Development of new probiotics by strain combinations: Is it possible to improve the adhesion to intestinal mucus?

M. C. Collado*, J. Meriluoto, S. Salminen

*Korresponderande författare för detta arbete

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

59 Citeringar (Scopus)

Sammanfattning

We evaluated the ability of commercial probiotic strains (Lactobacillus rhamnosus GG, L. rhamnosus LC705, Bifidobacterium breve 99, and Propionibacterium freudenreichii ssp. shermanii JS) to adhere alone or in different combinations to immobilized mucus. Probiotic combinations were clearly able to enhance the adhesion of L. rhamnosus GG, L. rhamnosus LC705, and P. freudenreichii ssp. shermanii JS. For L. rhamnosus GG and P. freudenreichii JS, all the combinations significantly improved adhesion to intestinal mucus, from 29.7 to 34.9% and from 1.9 to 2.3%, respectively. The adhesion of L. rhamnosus LC 705 was improved from 0 to 46.4%. The adhesion of B. breve 99 was improved only in combination with L. rhamnosus GG and P. freudenreichii JS. Our results suggest that probiotic combinations could increase the beneficial health effects as compared with individual strains. Combinations of probiotic strains may therefore have synergistic adhesion effects, and such combinations also should be assessed in clinical studies.

OriginalspråkEngelska
Sidor (från-till)2710-2716
Antal sidor7
TidskriftJournal of Dairy Science
Volym90
Utgåva6
DOI
StatusPublicerad - jun 2007
MoE-publikationstypA1 Tidskriftsartikel-refererad

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