Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

JHA Clubb; TV Kudling; M Girych; L Haybout; S Pakola; F Hamdan; V Cervera-Carrascon; A Hemmes; S Grönberg-Vähä-Koskela; JM Santos; DCA Quixabeira; S Basnet; C Heiniö; V Arias; E Jirovec; S Kaptan; R Havunen; S Sorsa; A Erikat; J Schwartz; M Anttila; K Aro; T Viitala; I Vattulainen; V Cerullo; A Kanerva; A Hemminki

doi:10.3389/fimmu.2023.1060540

Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

JHA Clubb, TV Kudling, M Girych, L Haybout, S Pakola, F Hamdan, V Cervera-Carrascon, A Hemmes, S Grönberg-Vähä-Koskela, JM Santos, DCA Quixabeira, S Basnet, C Heiniö, V Arias, E Jirovec, S Kaptan, R Havunen, S Sorsa, A Erikat, J SchwartzM Anttila, K Aro, T Viitala, I Vattulainen, V Cerullo, A Kanerva, A Hemminki

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

3 Citeringar (Scopus)

Originalspråk	Engelska
Artikelnummer	1060540
Antal sidor	20
Tidskrift	Frontiers in Immunology
Volym	14
DOI	https://doi.org/10.3389/fimmu.2023.1060540
Status	Publicerad - 3 feb. 2023
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

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10.3389/fimmu.2023.1060540

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Clubb, JHA., Kudling, TV., Girych, M., Haybout, L., Pakola, S., Hamdan, F., Cervera-Carrascon, V., Hemmes, A., Grönberg-Vähä-Koskela, S., Santos, JM., Quixabeira, DCA., Basnet, S., Heiniö, C., Arias, V., Jirovec, E., Kaptan, S., Havunen, R., Sorsa, S., Erikat, A., ... Hemminki, A. (2023). Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting. Frontiers in Immunology, 14, Artikel 1060540. https://doi.org/10.3389/fimmu.2023.1060540

@article{408a240717e646e99ed5bbfd7c6af390,

title = "Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting",

keywords = "PDAC, Syrian hamster, Adenovirus, Artificial intelligence, Immune checkpoint inhibitor, Immunotherapy, Molecular simulations, Oncolytic virus",

author = "JHA Clubb and TV Kudling and M Girych and L Haybout and S Pakola and F Hamdan and V Cervera-Carrascon and A Hemmes and S Gr{\"o}nberg-V{\"a}h{\"a}-Koskela and JM Santos and DCA Quixabeira and S Basnet and C Heini{\"o} and V Arias and E Jirovec and S Kaptan and R Havunen and S Sorsa and A Erikat and J Schwartz and M Anttila and K Aro and T Viitala and I Vattulainen and V Cerullo and A Kanerva and A Hemminki",

year = "2023",

month = feb,

day = "3",

doi = "10.3389/fimmu.2023.1060540",

language = "English",

volume = "14",

journal = "Frontiers in Immunology",

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Clubb, JHA, Kudling, TV, Girych, M, Haybout, L, Pakola, S, Hamdan, F, Cervera-Carrascon, V, Hemmes, A, Grönberg-Vähä-Koskela, S, Santos, JM, Quixabeira, DCA, Basnet, S, Heiniö, C, Arias, V, Jirovec, E, Kaptan, S, Havunen, R, Sorsa, S, Erikat, A, Schwartz, J, Anttila, M, Aro, K, Viitala, T, Vattulainen, I, Cerullo, V, Kanerva, A & Hemminki, A 2023, 'Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting', Frontiers in Immunology, vol. 14, 1060540. https://doi.org/10.3389/fimmu.2023.1060540

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T1 - Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting

AU - Clubb, JHA

AU - Kudling, TV

AU - Girych, M

AU - Haybout, L

AU - Pakola, S

AU - Hamdan, F

AU - Cervera-Carrascon, V

AU - Hemmes, A

AU - Grönberg-Vähä-Koskela, S

AU - Santos, JM

AU - Quixabeira, DCA

AU - Basnet, S

AU - Heiniö, C

AU - Arias, V

AU - Jirovec, E

AU - Kaptan, S

AU - Havunen, R

AU - Sorsa, S

AU - Erikat, A

AU - Schwartz, J

AU - Anttila, M

AU - Aro, K

AU - Viitala, T

AU - Vattulainen, I

AU - Cerullo, V

AU - Kanerva, A

AU - Hemminki, A

PY - 2023/2/3

Y1 - 2023/2/3

KW - PDAC

KW - Syrian hamster

KW - Adenovirus

KW - Artificial intelligence

KW - Immune checkpoint inhibitor

KW - Immunotherapy

KW - Molecular simulations

KW - Oncolytic virus

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U2 - 10.3389/fimmu.2023.1060540

DO - 10.3389/fimmu.2023.1060540

M3 - Article

C2 - 36817448

SN - 1664-3224

VL - 14

JO - Frontiers in Immunology

JF - Frontiers in Immunology

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