Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

Filip S. Ekholm; Ágnes Berényi; Lucas Lagerquist; Tiina Saloranta-Simell; István Zupkó; Gyula Schneider; János Wölfling; Reko Leino

doi:10.1016/j.carres.2012.03.017

Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

Filip S. Ekholm, Ágnes Berényi, Lucas Lagerquist, Tiina Saloranta-Simell, István Zupkó, Gyula Schneider, János Wölfling, Reko Leino

Molekylärvetenskap och -teknik

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

6 Citeringar (Scopus)

Sammanfattning

Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.

Originalspråk	Odefinierat/okänt
Sidor (från-till)	295–298
Antal sidor	4
Tidskrift	Carbohydrate Research
Volym	356
DOI	https://doi.org/10.1016/j.carres.2012.03.017
Status	Publicerad - 2012
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Nyckelord

Anthracyclines
Cytotoxic activity
Glycoconjugates
Saponins

Åtkomst av dokument

10.1016/j.carres.2012.03.017

Citera det här

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title = "Cytotoxic activity of some glycoconjugates including saponins and anthracyclines",

abstract = "Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.",

keywords = "Anthracyclines, Cytotoxic activity, Glycoconjugates, Saponins, Anthracyclines, Cytotoxic activity, Glycoconjugates, Saponins, Anthracyclines, Cytotoxic activity, Glycoconjugates, Saponins",

author = "Ekholm, {Filip S.} and {\'A}gnes Ber{\'e}nyi and Lucas Lagerquist and Tiina Saloranta-Simell and Istv{\'a}n Zupk{\'o} and Gyula Schneider and J{\'a}nos W{\"o}lfling and Reko Leino",

year = "2012",

doi = "10.1016/j.carres.2012.03.017",

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T1 - Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

AU - Ekholm, Filip S.

AU - Berényi, Ágnes

AU - Lagerquist, Lucas

AU - Saloranta-Simell, Tiina

AU - Zupkó, István

AU - Schneider, Gyula

AU - Wölfling, János

AU - Leino, Reko

PY - 2012

Y1 - 2012

N2 - Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.

AB - Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.

KW - Anthracyclines

KW - Cytotoxic activity

KW - Glycoconjugates

KW - Saponins

KW - Anthracyclines

KW - Cytotoxic activity

KW - Glycoconjugates

KW - Saponins

KW - Anthracyclines

KW - Cytotoxic activity

KW - Glycoconjugates

KW - Saponins

U2 - 10.1016/j.carres.2012.03.017

DO - 10.1016/j.carres.2012.03.017

M3 - Artikel

SN - 0008-6215

VL - 356

SP - 295

EP - 298

JO - Carbohydrate Research

JF - Carbohydrate Research

ER -