Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

Filip S. Ekholm, Ágnes Berényi, Lucas Lagerquist, Tiina Saloranta-Simell, István Zupkó, Gyula Schneider, János Wölfling, Reko Leino

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

4 Citeringar (Scopus)

Sammanfattning

Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.
OriginalspråkOdefinierat/okänt
Sidor (från-till)295–298
Antal sidor4
TidskriftCarbohydrate Research
Volym356
DOI
StatusPublicerad - 2012
MoE-publikationstypA1 Tidskriftsartikel-refererad

Nyckelord

  • Anthracyclines
  • Cytotoxic activity
  • Glycoconjugates
  • Saponins

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