Continuous enantioselective hydrogenation of ethylbenzoylformate over Pt/Al2O3 catalyst: Bed dilution effects and cinchonidine adsorption study

E. Toukoniitty, P. Mäki-Arvela, N. Kumar, T. Salmi, D. Yu Murzin*

*Korresponderande författare för detta arbete

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

24 Citeringar (Scopus)

Sammanfattning

Depending on the reaction medium (toluene or acetic acid) striking differences were observed in the development of enantiomeric excess with time-on-stream in continuous enantioselective hydrogenation of ethylbenzoylformate on cinchonidine-modified Pt/Al2O3, which correlated well with the amount of adsorbed cinchonidine on alumina and silica from acetic acid and toluene solutions. Maximally 93% enantiometric excess (ee) of (R)-ethyl mandelate was obtained.

OriginalspråkEngelska
Sidor (från-till)179-183
Antal sidor5
TidskriftCatalysis Letters
Volym95
Utgåva3-4
DOI
StatusPublicerad - jun 2004
MoE-publikationstypA1 Tidskriftsartikel-refererad

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