Comparative safety evaluation of silica-based particles

H Kettiger, Didem Sen Karaman, L Schiesser, Jessica Rosenholm, J Huwyler

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

27 Citeringar (Scopus)

Sammanfattning

Silica nanoparticles (SNPs) are increasingly used as drug delivery systems (DDS) and for biomedical imaging. Therapeutic and diagnostic agents can be incorporated into the silica matrix to improve the stability and dissolution of drug substances in biological systems. However, the safety of SNPs as drug carriers remains controversial. To date, no validated and accepted nano-specific tests exist to predict the potentially harmful impact of these materials on the human body.
OriginalspråkOdefinierat/okänt
Sidor (från-till)355–363
TidskriftToxicology in Vitro
Volym30
Utgåva1
DOI
StatusPublicerad - 2015
MoE-publikationstypA1 Tidskriftsartikel-refererad

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