Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review

Levente L. Simon; Hajnalka Pataki; György Marosi; Fabian Meemken; Konrad Hungerbühler; Alfons Baiker; Srinivas Tummala; Brian Glennon; Martin Kuentz; Gerry Steele; Herman J. M. Kramer; James W. Rydzak; Zengping Chen; Julian Morris; Francois Kjell; Ravendra Singh; Rafiqul Gani; Krist V. Gernaey; Marjatta Louhi-Kultanen; John O’Reilly; Niklas Sandler; Osmo Antikainen; Jouko Yliruusi; Patrick Frohberg; Joachim Ulrich; Richard D. Braatz; Tom Leyssens; Moritz von Stosch; Rui Oliveira; Reginald B. H. Tan; Wu Huiquan; Mansoor Khan; Des O’Grady; Anjan Pandey; Remko Westra; Emmanuel Delle-Case; Detlef Pape; Daniele Angelosante; Yannick Maret; Olivier Steiger; Miklós Lenner; Kaoutar Abbou-Oucherif; Zoltan K. Nagy; James D. Litster; Vamsi Krishna Kamaraju; Min-Sen Chiu

doi:10.1021/op500261y

Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review

Levente L. Simon
, Hajnalka Pataki
, György Marosi
, Fabian Meemken
, Konrad Hungerbühler
, Alfons Baiker
, Srinivas Tummala
, Brian Glennon
, Martin Kuentz
, Gerry Steele
, Herman J. M. Kramer
, James W. Rydzak
, Zengping Chen
, Julian Morris
, Francois Kjell
, Ravendra Singh
, Rafiqul Gani
, Krist V. Gernaey
, Marjatta Louhi-Kultanen
, John O’Reilly

Niklas Sandler, Osmo Antikainen, Jouko Yliruusi, Patrick Frohberg, Joachim Ulrich, Richard D. Braatz, Tom Leyssens, Moritz von Stosch, Rui Oliveira, Reginald B. H. Tan, Wu Huiquan, Mansoor Khan, Des O’Grady, Anjan Pandey, Remko Westra, Emmanuel Delle-Case, Detlef Pape, Daniele Angelosante, Yannick Maret, Olivier Steiger, Miklós Lenner, Kaoutar Abbou-Oucherif, Zoltan K. Nagy, James D. Litster, Vamsi Krishna Kamaraju, Min-Sen Chiu

Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review

429 Citeringar (Scopus)

Sammanfattning

This multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based process monitoring and control methods) and presenting applications both in industrial laboratories and in manufacture e.g. at GSK, AstraZeneca and Roche. Furthermore, the paper discusses the PAT paradigm from the regulatory science perspective. Given the multidisciplinary nature of PAT, such an endeavour would be almost impossible for a single author, so the concept of a multiauthor review was born. Each section of the multiauthor review has been written by a single expert or group of experts with the aim to report on its own research results. This paper also serves as a comprehensive source of information on PAT topics for the novice reader.

Originalspråk	Odefinierat/okänt
Sidor (från-till)	3–62
Tidskrift	Organic Process Research and Development
Volym	19
Nummer	1
DOI	https://doi.org/10.1021/op500261y
Status	Publicerad - 2015
MoE-publikationstyp	A2 Översiktsartikel artikel i en vetenskaplig tidskrift

Nyckelord

Process Analytical Technology (PAT)

Åtkomst av dokument

10.1021/op500261y

Citera det här

Simon, L. L., Pataki, H., Marosi, G., Meemken, F., Hungerbühler, K., Baiker, A., Tummala, S., Glennon, B., Kuentz, M., Steele, G., M. Kramer, H. J., Rydzak, J. W., Chen, Z., Morris, J., Kjell, F., Singh, R., Gani, R., Gernaey, K. V., Louhi-Kultanen, M., ... Chiu, M.-S. (2015). Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review. Organic Process Research and Development, 19(1), 3–62. https://doi.org/10.1021/op500261y

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abstract = "This multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based process monitoring and control methods) and presenting applications both in industrial laboratories and in manufacture e.g. at GSK, AstraZeneca and Roche. Furthermore, the paper discusses the PAT paradigm from the regulatory science perspective. Given the multidisciplinary nature of PAT, such an endeavour would be almost impossible for a single author, so the concept of a multiauthor review was born. Each section of the multiauthor review has been written by a single expert or group of experts with the aim to report on its own research results. This paper also serves as a comprehensive source of information on PAT topics for the novice reader.",

keywords = "Process Analytical Technology (PAT), Process Analytical Technology (PAT), Process Analytical Technology (PAT)",

author = "Simon, \{Levente L.\} and Hajnalka Pataki and Gy{\"o}rgy Marosi and Fabian Meemken and Konrad Hungerb{\"u}hler and Alfons Baiker and Srinivas Tummala and Brian Glennon and Martin Kuentz and Gerry Steele and \{M. Kramer\}, \{Herman J.\} and Rydzak, \{James W.\} and Zengping Chen and Julian Morris and Francois Kjell and Ravendra Singh and Rafiqul Gani and Gernaey, \{Krist V.\} and Marjatta Louhi-Kultanen and John O{\textquoteright}Reilly and Niklas Sandler and Osmo Antikainen and Jouko Yliruusi and Patrick Frohberg and Joachim Ulrich and Braatz, \{Richard D.\} and Tom Leyssens and \{von Stosch\}, Moritz and Rui Oliveira and \{H. Tan\}, \{Reginald B.\} and Wu Huiquan and Mansoor Khan and Des O{\textquoteright}Grady and Anjan Pandey and Remko Westra and Emmanuel Delle-Case and Detlef Pape and Daniele Angelosante and Yannick Maret and Olivier Steiger and Mikl{\'o}s Lenner and Kaoutar Abbou-Oucherif and Nagy, \{Zoltan K.\} and Litster, \{James D.\} and \{Krishna Kamaraju\}, Vamsi and Min-Sen Chiu",

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Simon, LL, Pataki, H, Marosi, G, Meemken, F, Hungerbühler, K, Baiker, A, Tummala, S, Glennon, B, Kuentz, M, Steele, G, M. Kramer, HJ, Rydzak, JW, Chen, Z, Morris, J, Kjell, F, Singh, R, Gani, R, Gernaey, KV, Louhi-Kultanen, M, O’Reilly, J, Sandler, N, Antikainen, O, Yliruusi, J, Frohberg, P, Ulrich, J, Braatz, RD, Leyssens, T, von Stosch, M, Oliveira, R, H. Tan, RB, Huiquan, W, Khan, M, O’Grady, D, Pandey, A, Westra, R, Delle-Case, E, Pape, D, Angelosante, D, Maret, Y, Steiger, O, Lenner, M, Abbou-Oucherif, K, Nagy, ZK, Litster, JD, Krishna Kamaraju, V & Chiu, M-S 2015, 'Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review', Organic Process Research and Development, vol. 19, nr. 1, s. 3–62. https://doi.org/10.1021/op500261y

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AU - Simon, Levente L.

AU - Pataki, Hajnalka

AU - Marosi, György

AU - Meemken, Fabian

AU - Hungerbühler, Konrad

AU - Baiker, Alfons

AU - Tummala, Srinivas

AU - Glennon, Brian

AU - Kuentz, Martin

AU - Steele, Gerry

AU - M. Kramer, Herman J.

AU - Rydzak, James W.

AU - Chen, Zengping

AU - Morris, Julian

AU - Kjell, Francois

AU - Singh, Ravendra

AU - Gani, Rafiqul

AU - Gernaey, Krist V.

AU - Louhi-Kultanen, Marjatta

AU - O’Reilly, John

AU - Sandler, Niklas

AU - Antikainen, Osmo

AU - Yliruusi, Jouko

AU - Frohberg, Patrick

AU - Ulrich, Joachim

AU - Braatz, Richard D.

AU - Leyssens, Tom

AU - von Stosch, Moritz

AU - Oliveira, Rui

AU - H. Tan, Reginald B.

AU - Huiquan, Wu

AU - Khan, Mansoor

AU - O’Grady, Des

AU - Pandey, Anjan

AU - Westra, Remko

AU - Delle-Case, Emmanuel

AU - Pape, Detlef

AU - Angelosante, Daniele

AU - Maret, Yannick

AU - Steiger, Olivier

AU - Lenner, Miklós

AU - Abbou-Oucherif, Kaoutar

AU - Nagy, Zoltan K.

AU - Litster, James D.

AU - Krishna Kamaraju, Vamsi

AU - Chiu, Min-Sen

PY - 2015

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AB - This multiauthor review article aims to bring readers up to date with some of the current trends in the field of process analytical technology (PAT) by summarizing each aspect of the subject (sensor development, PAT based process monitoring and control methods) and presenting applications both in industrial laboratories and in manufacture e.g. at GSK, AstraZeneca and Roche. Furthermore, the paper discusses the PAT paradigm from the regulatory science perspective. Given the multidisciplinary nature of PAT, such an endeavour would be almost impossible for a single author, so the concept of a multiauthor review was born. Each section of the multiauthor review has been written by a single expert or group of experts with the aim to report on its own research results. This paper also serves as a comprehensive source of information on PAT topics for the novice reader.

KW - Process Analytical Technology (PAT)

U2 - 10.1021/op500261y

DO - 10.1021/op500261y

M3 - Översiktsartikel

SN - 1083-6160

VL - 19

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JO - Organic Process Research and Development

JF - Organic Process Research and Development

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