An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit <i>KRAS</i> Mutant Cancer Cell Growth

Pelin Kaya; Elisabeth Schaffner-Reckinger; Ganesh babu Manoharan; Vladimir Vukic; Alexandros Kiriazis; Mirko Ledda; Maria Burgos Renedo; Karolina Pavic; Anthoula Gaigneaux; Enrico Glaab; Daniel Kwaku Abankwa

doi:10.1021/acs.jmedchem.3c02129

An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit <i>KRAS</i> Mutant Cancer Cell Growth

Pelin Kaya
, Elisabeth Schaffner-Reckinger
, Ganesh babu Manoharan
, Vladimir Vukic
, Alexandros Kiriazis
, Mirko Ledda
, Maria Burgos Renedo
, Karolina Pavic
, Anthoula Gaigneaux
, Enrico Glaab
, Daniel Kwaku Abankwa

Åbo biovetenskapscentrum

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

19 Citeringar (Scopus)

77 Nedladdningar (Pure)

Originalspråk	Engelska
Sidor (från-till)	8569-8584
Antal sidor	16
Tidskrift	Journal of Medicinal Chemistry
Volym	67
Nummer	11
DOI	https://doi.org/10.1021/acs.jmedchem.3c02129
Status	Publicerad - 17 maj 2024
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Nyckelord

Assays
Toxicological synergy
Inhibitors
Cells
Bioluminescence

Åtkomst av dokument

10.1021/acs.jmedchem.3c02129Licens: CC BY

kaya-et-al-2024-an-improved-pde6d-inhibitor-combines-with-sildenafil-to-inhibit-kras-mutant-cancer-cell-growthSlutlig publicerad version, 5,5 MBLicens: CC BY

https://urn.fi/URN:NBN:fi-fe2025020710463

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title = "An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth",

keywords = "Assays, Toxicological synergy, Inhibitors, Cells, Bioluminescence",

author = "Pelin Kaya and Elisabeth Schaffner-Reckinger and Manoharan, \{Ganesh babu\} and Vladimir Vukic and Alexandros Kiriazis and Mirko Ledda and \{Burgos Renedo\}, Maria and Karolina Pavic and Anthoula Gaigneaux and Enrico Glaab and Abankwa, \{Daniel Kwaku\}",

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T1 - An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth

AU - Kaya, Pelin

AU - Schaffner-Reckinger, Elisabeth

AU - Manoharan, Ganesh babu

AU - Vukic, Vladimir

AU - Kiriazis, Alexandros

AU - Ledda, Mirko

AU - Burgos Renedo, Maria

AU - Pavic, Karolina

AU - Gaigneaux, Anthoula

AU - Glaab, Enrico

AU - Abankwa, Daniel Kwaku

PY - 2024/5/17

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KW - Toxicological synergy

KW - Inhibitors

KW - Cells

KW - Bioluminescence

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DO - 10.1021/acs.jmedchem.3c02129

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EP - 8584

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

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