Sammanfattning
The fibrous polymer-supported sulfonic acid catalyst Smopex-101 H(+) proved to be an efficient catalyst for the preparation of O-isopropylidene derivatives from a series of rare sugars. Acetonation of the reducing sugars L-arabinose, L-ribose, L-xylose, L-fucose, and L-rhamnose in N,N-dimethylformamide by 2,2-dimethoxypropane or 2-methoxypropene led to the formation of the kinetically favored di-O- and/or mono-O-isopropylidene derivatives in 46-88% yields. The method consists of a simple experimental procedure which does not require predried solvents or reagents. The catalyst is easily recovered and can be regenerated making the procedure economically viable even for large-scale synthesis.
Originalspråk | Odefinierat/okänt |
---|---|
Sidor (från-till) | 1548–1554 |
Antal sidor | 7 |
Tidskrift | Carbohydrate Research |
Volym | 345 |
Nummer | 11 |
DOI | |
Status | Publicerad - 2010 |
MoE-publikationstyp | A1 Tidskriftsartikel-refererad |
Nyckelord
- Acetonation
- Heterogeneous catalysis
- Isopropylidene acetals
- Kinetic control
- L-Carbohydrates