Targeted delivery of CRISPR/Cas9 for advanced liver cancer therapy through c-Myc knockout

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Publikationer per år 2020 2022 2023

• 35 Artikel
• 6 Översiktsartikel

Publikationer per år

Publikationer per år

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• 2023

  A pH/temperature responsive nanocomposite for chemo-photothermal synergistic cancer therapy

  Mustafa, R. A., Ran, M., Wang, Y., Yan, J., Zhang, Y., Rosenholm, J. M. & Zhang, H., 2023, I: Smart Materials in Medicine. 4, s. 199-211 13 s.

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  • Nanocomposite 100%
  • Doxorubicin 83%
  • Mesoporous Silica 50%
  • Breast Cancer 50%
  • Chemotherapy 50%
  16 Citeringar (Scopus)

  81 Nedladdningar (Pure)

• Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple negative breast cancers to predict clinical treatment

  Zheng, D., Zhou, J., Qian, L., Liu, X., Chang, C., Tang, S., Zhang, H. & Zhou, S., apr. 2023, I: Bioactive materials. 22, s. 567-587

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  • Shear 100%
  • Wave 100%
  • Elastic Property 100%
  • Elasticity 100%
  • Stiffness 87%
  10 Citeringar (Scopus)

  28 Nedladdningar (Pure)
• 2022

  2D nanomaterial sensing array using machine learning for differential profiling of pathogenic microbial taxonomic identification

  Li, Z., Jiang, Y., Tang, S., Zou, H., Wang, W., Qi, G., Zhang, H., Jin, K., Wang, Y., Chen, H., Zhang, L. & Qu, X., aug. 2022, I: Microchimica Acta. 189, 8, 14 s., 273.

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  • Microorganism 100%
  • Detection 61%
  • Micro-Organism 50%
  • Response 44%
  • Array 27%
  6 Citeringar (Scopus)

  33 Nedladdningar (Pure)

• A molecularly imprinted antibiotic receptor on magnetic nanotubes for the detection and removal of environmental oxytetracycline

  Wang, J., Li, X., Zhang, R., Fu, B., Chen, M., Ye, M., Liu, W., Xu, J., Pan, G. & Zhang, H., 21 sep. 2022, I: Journal of Materials Chemistry. B. 10, 35, s. 6777-6783 7 s.

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  • Magnetism 100%
  • Chromatography 100%
  • Nanotube 100%
  • Fluorescence 50%
  • Copurification 50%
  9 Citeringar (Scopus)

  24 Nedladdningar (Pure)

• Bionic Microbubble Neutrophil Composite for Inflammation-Responsive Atherosclerotic Vulnerable Plaque Pluripotent Intervention

  Liu, F., Mao, Y., Yan, J., Sun, Y., Xie, Z., Li, F., Yan, F., Zhang, H. & Zhang, P., 3 juni 2022, I: Research. 2022, 11 s., 9830627.

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  • Neutrophil 100%
  • Vulnerable Plaque 100%
  • Lesion 66%
  • Drug 66%
  • Chemotherapeutic Agent 66%
  9 Citeringar (Scopus)

  61 Nedladdningar (Pure)

• Breaking the Iron Homeostasis: A “Trojan Horse” Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition

  Li, Y., Cen, Y., Fang, Y., Tang, S., Li, S., Ren, Y., Zhang, H., Lu, W. & Xu, J., 23 aug. 2022, I: ACS Nano. 16, 8, s. 12786-12800 15 s.

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  • Ovarian Cancer 100%
  • Homologous Recombination 100%
  • Olaparib 100%
  • Recombination Repair 85%
  • Cancer Cell 57%
  5 Citeringar (Scopus)

  54 Nedladdningar (Pure)

• Ca2+ enhanced photosensitizer/DNase I nanocomposite mediated bacterial eradication through biofilm disruption and photothermal therapy

  Ran, M., Gounani, Z., Yan, J., Rosenholm, J. M. & Zhang, H., 16 apr. 2022, I: Nano Select. 11 s.

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  • Deoxyribonuclease I 100%
  • Bacterium 60%
  • Calcium Ion 60%
  • Photothermal Therapy 60%
  • Nanocomposite 60%
  54 Nedladdningar (Pure)

• Co‐delivery CPT and PTX prodrug with a photo/thermo‐responsive nanoplatform for triple‐negative breast cancer therapy

  Zhou, W., Ma, X., Wang, J., Xu, X., Koivisto, O., Feng, J., Viitala, T. & Zhang, H., 27 dec. 2022, I: Smart Medicine.

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  37 Nedladdningar (Pure)

• Co-Delivery of Paclitaxel Prodrug, Gemcitabine and Porphine by Micelles for Pancreatic Cancer Treatment via Chemo-Photodynamic Combination Therapy

  Wu, Q., Ma, X., Zhou, W., Yu, R., Rosenholm, J. M., Tian, W., Zhang, L., Wang, D. & Zhang, H., nov. 2022, I: Pharmaceutics. 14, 11, 16 s., 2280.

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  • Paclitaxel 100%
  • Gemcitabine 100%
  • Pancreas Cancer 80%
  • Prodrug 80%
  • Nitrogen Mustard 60%
  4 Citeringar (Scopus)

  42 Nedladdningar (Pure)

• Combination of photothermal, prodrug and tumor cell camouflage technologies for triple-negative breast cancer treatment

  Zhang, L., Ma, X., Zhou, W., Wu, Q., Yan, J., Xu, X., Ghimire, B., Rosenholm, J. M., Feng, J., Wang, D. & Zhang, H., mars 2022, I: Materials Today Advances. 13, 100199.

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  • Doxorubicin 100%
  • Paclitaxel 66%
  • Prodrug 66%
  • Triple Negative Breast Cancer 66%
  • Neoplasm 50%
  16 Citeringar (Scopus)

  77 Nedladdningar (Pure)

• Efficient nanozyme engineering for antibacterial therapy

  Feng, Y., Chen, F., Rosenholm, J. M., Liu, L. & Zhang, H., 28 juni 2022, I: Materials Futures. 1, 2

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  • Antiinfective Agent 100%
  • Antimicrobial Resistance 80%
  • Enzymatic Activity 60%
  • External Stimulus 20%
  • Enhancement 20%
  12 Citeringar (Scopus)

  17 Nedladdningar (Pure)

• Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy

  Zhang, J., Ji, C., Zhang, H., Shi, H., Mao, F., Qian, H., Xu, W., Wang, D., Pan, J., Fang, X., Santos, H. A. & Zhang, X., 14 jan. 2022, I: Science Advances. 8, 2, eabj8207.

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  • Tumor 100%
  • Neoplasm 85%
  • Doxorubicin 42%
  • Nanoparticle 28%
  • Iron Oxide 28%
  104 Citeringar (Scopus)

  12 Nedladdningar (Pure)

• Helper T Cell (CD4+) Targeted Tacrolimus Delivery Mediates Precise Suppression of Allogeneic Humoral Immunity

  Shen, J., Liu, C., Yan, P., Wang, M., Guo, L., Liu, S., Chen, J., Rosenholm, J. M., Huang, H., Wang, R. & Zhang, H., 19 juli 2022, I: Research. 2022, 15 s., 9794235.

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  • Tacrolimus 100%
  • T Follicular Helper Cell 100%
  • Obstetric Delivery 100%
  • Side Effect 75%
  • Antibody 75%
  7 Citeringar (Scopus)

  29 Nedladdningar (Pure)

• Interactions between polymeric nanoparticles and different buffers as investigated by zeta potential measurements and molecular dynamics simulations

  Inam, W., Bhadane, R., Akpolat, R. N., Taiseer, R. A., Filippov, S. K., Salo-Ahen, O. M. H., Rosenholm, J. M. & Zhang, H., 21 feb. 2022, I: VIEW. s. 1-21 21 s.

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  • Zeta Potential 100%
  • Nanoparticle 44%
  • Gas Fuel Measurement 16%
  • Solution 16%
  • Polymer Nanoparticles 16%
  15 Citeringar (Scopus)

  220 Nedladdningar (Pure)

• In Vivo Kidney Allograft Endothelial Specific Scavengers for On‐Site Inflammation Reduction under Antibody‐Mediated Rejection

  Liu, C., Yan, P., Xu, X., Zhou, W., Rajan Prakash, D., Wang, S., Wang, R., Huang, H., Chen, J., Zhang, H. & Shen, J., 8 sep. 2022, I: Small. 18, 36, 2106746.

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  • Antibody Mediated Rejection 100%
  • Endothelium 75%
  • Allotransplantation 75%
  • Kidney 50%
  • Scavenger 50%
  3 Citeringar (Scopus)

  32 Nedladdningar (Pure)

• Microfluidic-assisted biomineralization of CRISPR/Cas9 in near-infrared responsive metal–organic frameworks for programmable gene-editing

  Xu, X., Liu, C., Wang, S., Mäkilä, E., Wang, J., Koivisto, O., Zhou, J., Rosenholm, J. M., Shu, Y. & Zhang, H., 12 okt. 2022, I: Nanoscale. 14, 42, s. 15832-15844 13 s.

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  • Microfluidics 100%
  • Biomineralization 60%
  • Time 30%
  • Application 20%
  • Potential 20%
  8 Citeringar (Scopus)

  25 Nedladdningar (Pure)

• Mussel-Inspired and Bioclickable Peptide Engineered Surface to Combat Thrombosis and Infection

  Mou, X., Zhang, H., Qiu, H., Zhang, W., Wang, Y., Xiong, K., Huang, N., Santos, H. A. & Yang, Z., 14 apr. 2022, I: Research. 2022, 9780879.

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  • Surface 100%
  • Peptide 50%
  • Device 33%
  • Copper Ion 33%
  • Biomimetics 33%
  28 Citeringar (Scopus)

  124 Nedladdningar (Pure)

• Reregulated mitochondrial dysfunction reverses cisplatin resistance microenvironment in colorectal cancer

  Wang, Y., Ma, X., Zhou, W., Liu, C. & Zhang, H., 22 dec. 2022, I: Smart Medicine. 1, 1

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  • Neoplasm 100%
  • Cisplatin 57%
  • Chemotherapy 42%
  • Drug Resistance 28%
  • Malignant Neoplasm 28%
  26 Nedladdningar (Pure)

• Self-assembly of DNA nanogels with endogenous microRNA toehold self-regulating switches for targeted gene regulation therapy

  Yan, J., Zou, H., Zhou, W., Yuan, X., Li, Z., Ma, X., Liu, C., Wang, Y., Rosenholm, J. M., Cui, W., Qu, X. & Zhang, H., 20 juni 2022, I: Biomaterials Science. 10, 15, s. 4119-4125 7 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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  • microRNA 21 100%
  • Drug Release 50%
  • Mesoporous Silica Nanoparticle 50%
  • DNA 50%
  • Nanogel 50%
  12 Citeringar (Scopus)

  10 Nedladdningar (Pure)

• Silica Nanoparticles with Virus-Mimetic Spikes Enable Efficient siRNA Delivery In Vitro and In Vivo

  Fu, J., Han, W., Zhang, X., Sun, Y., Bhadane, R., Wei, B., Li, L., Yu, L., Yang, J., Rosenholm, J. M., Salo-Ahen, O. M. H., Fan, T., Zhang, B., Swelm, W., Al-Ghamdi, A. A., Xia, L., Zhang, H., Qiu, M., Zhang, H. & Wang, X., 21 dec. 2022, I: Research.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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  • Spike 100%
  • Surface Property 33%
  • Length 33%
  • Virus 33%
  • Intracellular Trafficking 33%
  4 Citeringar (Scopus)

  9 Nedladdningar (Pure)

• Synthesis, characterization and biocompatibility of guar gum-benzoic acid

  Le, T-A., Guo, Y., Zhou, J-N., Yan, J., Zhang, H. & Huynh, T-P., 1 jan. 2022, I: International Journal of Biological Macromolecules. 194, s. 110-116

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  • Benzoic Acid 100%
  • Guar Gum 75%
  • Thermogravimetric Analysis 25%
  • X-Ray Diffraction 25%
  • Biocompatibility 25%
  10 Citeringar (Scopus)

  56 Nedladdningar (Pure)

• UiO-66-NH2 as a novel ultrahigh-selective adsorbent superior to molecularly imprinted polymers for the adsorption of artesunate

  Meng, M., Wang, S., Dai, J., Li, Y., Feng, Y., Zhu, Y., Zhang, H. & Li, Y., 5 juli 2022, I: Colloids and Surfaces A: Physicochemical and Engineering Aspects. 644, 128830.

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  • Adsorption 100%
  • Reaction Selectivity 26%
  • Molecularly Imprinted Polymer 20%
  • Hydrophobic Surface 20%
  • Hydrophilicity 13%
  5 Citeringar (Scopus)
• 2021

  Hybrid Nanoparticles for Haloperidol Encapsulation: Quid Est Optimum?

  Filippov, S. K., Khusnutdinov, R. R., Inham, W., Liu, C., Nikitin, D. O., Semina, I. I., Garvey, C. J., Nasibullin, S. F., Khutoryanskiy, V. V., Zhang, H. & Moustafine, R. I., 30 nov. 2021, I: Polymers. 13, 23, 4189.

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  • Haloperidol 100%
  • Drug 57%
  • Polyoxyethylene Oleyl Ether 57%
  • Eudragit 57%
  • Diseases 14%
  3 Citeringar (Scopus)

  49 Nedladdningar (Pure)

• Improving the knock-in efficiency of the MOF-encapsulated CRISPR/Cas9 system through controllable embedding structures

  Liu, C., Xu, X., Koivisto, O., Zhou, W., Jacquemet, G., Rosenholm, J. M. & Zhang, H., 1 sep. 2021, I: Nanoscale. 13, 39, s. 16525-16532 8 s.

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  • Metal Organic Framework 100%
  • Structure 66%
  • Clustered Regularly Interspaced Short Palindromic Repeat 50%
  • Nanomaterial 33%
  • Embedding 33%
  16 Citeringar (Scopus)

  27 Nedladdningar (Pure)

• Metal-organic framework (MOF)-based biomaterials in bone tissue engineering

  Liu, C., Xu, X., Cui, W. & Zhang, H., sep. 2021, I: Engineered Regeneration. 2

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  60 Citeringar (Scopus)

  202 Nedladdningar (Pure)

• Molecularly Imprinted Fluoroprobes Doped with Ag Nanoparticles for Highly Selective Detection of Oxytetracycline in Real Samples

  Wang, J., Zou, L., Xu, J., Zhang, R. & Zhang, H., 2021, I: Analytica Chimica Acta. 1161

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  17 Citeringar (Scopus)

  37 Nedladdningar (Pure)

• Multistage signal-interactive nanoparticles improve tumor targeting through efficient nanoparticle-cell communications

  Zhang, F., Zhang, Y., Kong, L., Luo, H., Zhang, Y., Mäkilä, E., Salonen, J., Hirvonen, J., Zhu, Y., Chen, Y., Deng, L., Zhang, H., Kros, A., Cui, W. & Santos, H. A., 2021, I: Cell Reports. 35, 8, 109131.

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  4 Citeringar (Scopus)

  37 Nedladdningar (Pure)

• Nanoparticle-based inner ear delivery systems for the treatment of hearing loss

  Xu, X., Wang, S., Shu, Y. & Zhang, H., nov. 2021, I: Smart Materials in Medicine. 2, s. 350-353

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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  • Hearing Impairment 100%
  • Nanoparticle 100%
  • Drug 40%
  • Bioconjugation 40%
  • Nanotechnology 40%
  10 Citeringar (Scopus)

  56 Nedladdningar (Pure)

• Peritumoral Microgel Reservoir for Long-Term Light-Controlled Triple-Synergistic Treatment of Osteosarcoma with Single Ultra-Low Dose

  Yan, J., Wang, Y., Ran, M., Mustafa, R., Luo, H., Wang, J., Smått, J-H., Rosenholm, J., Cui, W., Lu, Y., Guan, Z. & Zhang, H., 2021, I: Small. 17, 31, 2100479.

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  • Silicon Dioxide 100%
  • Drug 50%
  • Doxorubicin 50%
  • Adverse Drug Reaction 25%
  • Antiinfective Agent 25%
  41 Citeringar (Scopus)

  25 Nedladdningar (Pure)

• Programmable immune activating electrospun fibers for skin regeneration

  Chen, L., Zhang, L., Zhang, H., Sun, X., Liu, D., Zhang, J., Zhang, Y., Cheng, L., Santos, H. A. & Cui, W., 2021, I: Bioactive materials. 6, 10, s. 3218-3230

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  49 Citeringar (Scopus)

  32 Nedladdningar (Pure)

• Radiogenomic Analysis of Papillary Thyroid Carcinoma for Prediction of Cervical Lymph Node Metastasis: A Preliminary Study

  Tong, Y., Sun, P., Yong, J., Zhang, H., Huang, Y., Guo, Y., Yu, J., Zhou, S., Wang, Y., Wang, Y., Ji, Q., Wang, Y. & Zhang, C., 29 juni 2021, I: Frontiers in Oncology. 11, 682998.

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  • Gene 100%
  • Radiomics 88%
  • Nested Gene 88%
  • Neoplasm 66%
  • Papillary Thyroid Cancer 66%
  12 Citeringar (Scopus)

  37 Nedladdningar (Pure)
• 2020

  Construction of Dual-Biofunctionalized Chitosan/Collagen Scaffolds for Simultaneous Neovascularization and Nerve Regeneration

  Li, G., Han, Q., Lu, P., Zhang, L., Zhang, Y., Chen, S., Zhang, P., Zhang, L., Cui, W., Wang, H. & Zhang, H., aug. 2020, I: Research. 2020, 2603048.

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  • Vascularity 100%
  • Nerve Regeneration 100%
  • Vascularization 100%
  • Collagen 60%
  • Chitosan 60%
  40 Citeringar (Scopus)

• Delivery of Protein Kinase A by CRISPRMAX and Its Effects on Breast Cancer Stem-Like Properties

  Zhou, J-N., Rautio, T-C., Liu, C., Xu, X-Y., Wang, D-Q., Guo, Y., Eriksson, J. & Zhang, H., dec. 2020, I: Pharmaceutics. 13, 1

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  4 Citeringar (Scopus)

  80 Nedladdningar (Pure)

• Mineralization of pH-Sensitive Doxorubicin Prodrug in ZIF-8 to Enable Targeted Delivery to Solid Tumors

  Yan, J., Liu, C., Wu, Q., Zhou, J., Xu, X., Zhang, L., Wang, D., Yang, F. & Zhang, H., 18 aug. 2020, I: Analytical Chemistry. 92, 16, s. 11453-11461 9 s.

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  • Doxorubicin 100%
  • Prodrug 100%
  • Doxil 100%
  • Carboxyl Group 50%
  • Tenidap 50%
  63 Citeringar (Scopus)

  43 Nedladdningar (Pure)

• Self-crosslinkable chitosan-hyaluronic acid dialdehyde nanoparticles for CD44-targeted siRNA delivery to treat bladder cancer

  Liang, Y., Wang, Y., Wang, L., Liang, Z., Li, D., Xu, X., Chen, Y., Yang, X., Zhang, H. & Niu, H., 8 sep. 2020, I: Bioactive materials. 6, 2, s. 433-446 14 s.

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  108 Citeringar (Scopus)

  23 Nedladdningar (Pure)