Protein deficiencies in Parkinson´s



Disturbed proteostasis may contribute to Parkinson’s disesase where deficient clearance of misfolded alpha-synuclein contributes to the pathology. Cells under stress are affected by this by a variety of mechanisms. From translational infidelity to usage of alternative start sites, the resulting protein aberrancies remain undetected by standard proteomics methods. This project will apply new methods to re-analyse existing proteomic data from Parkinson’s patient cohorts to uncover hidden proteome aberrancies within.
Kort titelMJFF Datascience
Gällande start-/slutdatum01/06/2231/01/24


  • Michael J. Fox Foundation: 287 071,00 €