Publikationer per år
Publikationer per år
- 1 - 50 av 66 resultat
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2024
HSV-1 and Cellular miRNAs in CSF-Derived Exosomes as Diagnostically Relevant Biomarkers for Neuroinflammation
Scheiber, C., Klein, H. C., Schneider, J. M., Schulz, T., Bechter, K., Tumani, H., Kapapa, T., Flinkman, D., Coffey, E., Ross, D., Čistjakovs, M., Nora-Krūkle, Z., Bortolotti, D., Rizzo, R., Murovska, M. & Schneider, E. M., 17 juli 2024, I: Cells.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
1 Citeringar (Scopus) -
Jnk1 and downstream signalling hubs regulate anxiety-like behaviours in a zebrafish larvae phenotypic screen
Hong, Y., Sourander, C., Hackl, B., Patton, J., John, J., Paatero, I. & Coffey, E., 15 maj 2024, I: Scientific Reports.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång1 Citeringar (Scopus) -
2023
Regulators of proteostasis are translationally repressed in fibroblasts from patients with sporadic and LRRK2-G2019S Parkinson's disease
Flinkman, D., Hong, Y., Gnjatovic, J., Deshpande, P., Ortutay, Z., Peltonen, S., Kaasinen, V., James, P. & Coffey, E., 6 feb. 2023, I: NPJ Parkinson's disease. 9, 1, s. 20Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil5 Citeringar (Scopus)85 Nedladdningar (Pure) -
2022
Long-term osteogenic differentiation of human bone marrow stromal cells in simulated microgravity: novel proteins sighted
Montagna, G., Pani, G., Flinkman, D., Cristofaro, F., Pascucci, B., Massimino, L., Lamparelli, L. A., Fassina, L., James, P., Coffey, E., Rea, G., Visai, L. & Rizzo, A. M., 1 okt. 2022, I: Cellular and Molecular Life Sciences. 79, 10, 536.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil5 Citeringar (Scopus)23 Nedladdningar (Pure) -
PhosPiR: an automated phosphoproteomic pipeline in R
Hong, Y., Flinkman, D., Suomi, T., Pietilä, S., James, P., Coffey, E. & Elo, L. L., jan. 2022, I: Briefings in Bioinformatics. 23, 1Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil7 Citeringar (Scopus)48 Nedladdningar (Pure) -
2021
SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling
Salomaa, S. I., Miihkinen, M., Kremneva, E., Paatero, I., Lilja, J., Jacquemet, G., Vuorio, J., Antenucci, L., Kogan, K., Hassani Nia, F., Hollos, P., Isomursu, A., Vattulainen, I., Coffey, E. T., Kreienkamp, H.-J., Lappalainen, P. & Ivaska, J., 22 nov. 2021, I: Current Biology. 31, 22, s. 4956-4970.e9Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång17 Citeringar (Scopus) -
2020
Impact of JNK and Its Substrates on Dendritic Spine Morphology
Komulainen, E., Varidaki, A., Kulesskaya, N., Mohammad, H., Sourander, C., Rauvala, H. & Coffey, E. T., 14 feb. 2020, I: Cells. 9, 2Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång13 Citeringar (Scopus) -
Optogenetic control of spine-head JNK reveals a role in dendritic spine regression
Hollós, P., John, J. M., Lehtonen, J. & Coffey, E., 2020, I: eNeuro. 7, 1, s. –Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil10 Citeringar (Scopus)32 Nedladdningar (Pure) -
PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins
Santio, N. M., Vainio, V., Hoikkala, T., Mung, K. L., Lång, M., Vahakoski, R., Zdrojewska, J., Coffey, E. T., Kremneva, E., Rainio, E.-M. & Koskinen, P. J., 8 aug. 2020, I: Cell Communication and Signaling. 18, 1Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång14 Citeringar (Scopus) -
Protein synthesis is suppressed in sporadic and familial Parkinson's disease by LRRK2
Deshpande, P., Flinkman, D., Hong, Y., Goltseva, E., Siino, V., Sun, L., Peltonen, S., Elo, L. L., Kaasinen, V., James, P. & Coffey, E. T., nov. 2020, I: FASEB Journal. 34, 11, s. 14217-14233 17 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång16 Citeringar (Scopus) -
2019
L-alpha-amino adipic acid provokes depression-like behaviour and a stress related increase in dendritic spine density in the pre-limbic cortex and hippocampus in rodents
David, J., Gormley, S., McIntosh, A., Kebede, V., Thuery, G., Varidaki, A., Coffey, E. & Harkin, A., 2019, I: Behavioural Brain Research. 362, s. 90–102Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
19 Citeringar (Scopus) -
2018
A novel method for minimal non-invasive diagnosis of Parkinson’s Disease
Coffey, E. (Uppfinnare), Hong, Y. (Uppfinnare), Flinkman, D. (Uppfinnare), James, P. (Uppfinnare), Deshpande, P. (Uppfinnare), Kaasinen, V. (Uppfinnare) & Peltonen, S. (Uppfinnare), 21 juni 2018, Patentnr. WO/2018/109277Forskningsoutput: IPR rättigheter › Beviljad patent ägd av ÅA
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JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche
Mohammad, H., Marchisella, F., Ortega-Martinez, S., Hollos, P., Eerola, K., Komulainen, E., Kulesskaya, N., Freemantle, E., Fagerholm, V., Savontous, E., Rauvala, H., Peterson, B. D., van Praag, H. & Coffey, E. T., feb. 2018, I: Molecular Psychiatry. 23, 2, s. 487Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
1 Citeringar (Scopus) -
JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche
Mohammad, H., Marchisella, F., Ortega Martinez, S., Hollós, P., Eerola, K., Komulainen, E., Kulesskaya, N., Freemantle, E., Fagerholm, V., Savontaus, E., Rauvala, H., Peterson, B., van Praag, H. & Coffey, E., 2018, I: Molecular Psychiatry. 23, 2, s. 362–374Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
50 Citeringar (Scopus) -
JNK Regulation of Depression and Anxiety.
Hollós, P., Marchisella, F. & Coffey, E., 2018, I: Brain Plasticity. 3, 2, s. 145–155Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review
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Repositioning Microtubule Stabilizing Drugs for Brain Disorders.
Varidaki, A., Hong, Y. & Coffey, E., aug. 2018, I: Frontiers in Cellular Neuroscience. 12, s. –Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
52 Citeringar (Scopus) -
Synthesis of Azide-Modified Chondroitin Sulfate Precursors: Substrates for "Click"- Conjugation with Fluorescent Labels and Oligonucleotides.
Jadhav, S., Gulumkar, V., Deshpande, P., Coffey, E., Lönnberg, H. & Virta, P., 2018, I: Bioconjugate Chemistry. 29, 7, s. 2382–2393Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
11 Citeringar (Scopus) -
2016
JNK1 regulates adult hippocampal neurogenesis and controls anxiety and depressive behaviour.
Coffey, E., 2016.Forskningsoutput: Konferensbidrag › Sammanfattning › Vetenskaplig
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KIF5C S176 Phosphorylation Regulates Microtubule Binding and Transport Efficiency in Mammalian Neurons
Padzik, A., Deshpande, P., Hollós, P., Franker, M., Rannikko, E. H., Cai, D., Prus, P., Mågård, M., Westerlund, N., Verhey, K. J., James, P., Hoogenraad, C. C. & Coffey, E., 2016, I: Frontiers in Cellular Neuroscience. 10, s. 1–15Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
21 Citeringar (Scopus) -
Microtubule and microtubule associated protein anomalies in psychiatric disease
Marchisella, F., Coffey, E. & Hollós, P., 2016, I: Cytoskeleton. 73, 10, s. 596–611Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review
86 Citeringar (Scopus) -
Molecular Mechanisms of Depression
Varidaki, A., Mohammad, H. & Coffey, E., 2016, Systems Neuroscience in Depression. Frodl, T. (red.). Academic Press, s. 143-178Forskningsoutput: Kapitel i bok/konferenshandling › Kapitel › Vetenskaplig › Peer review
6 Citeringar (Scopus) -
2014
CANDLES, an assay for monitoring GPCR induced cAMP generation in cell cultures.
Trehan, A., Rotgers, E., Coffey, E., Huhtaniemi, I. & Rivero-Müller, A., nov. 2014, I: Cell communication and signaling : CCS.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
19 Citeringar (Scopus) -
JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination.
Komulainen, E., Zdrojewska, J., Freemantle, E., Mohammad, H., Kulesskaya, N., Deshpande, P., Marchisella, F., Mysore, R., Hollos, P., Michelsen, K., Mågard, M. & Coffey, E., sep. 2014, I: Frontiers in Cellular Neuroscience.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
26 Citeringar (Scopus) -
Nuclear and cytosolic JNK signalling in neurons.
Coffey, E., maj 2014, I: Nature reviews. Neuroscience.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
250 Citeringar (Scopus) -
The impact of JNK on neuronal migration.
Zdrojewska, J. & Coffey, E., jan. 2014, I: Advances in Experimental Medicine and Biology.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
7 Citeringar (Scopus) -
2013
Translocation of Vibrio parahaemolyticus across an in vitro M cell model.
Finn, R., Ahmad, T., Coffey, E., Brayden, D., Baird, A. & Boyd, A., nov. 2013, I: FEMS Microbiology Letters.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
10 Citeringar (Scopus) -
2012
c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells.
Björkblom, B., Padzik, A., Mohammad, H., Westerlund, N., Komulainen, E., Hollos, P., Parviainen, L., Papageorgiou, A., Iljin, K., Kallioniemi, O., Kallajoki, M. & Coffey, E., juli 2012, I: Molecular and Cellular Biology.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
67 Citeringar (Scopus) -
The prognostic value of MARCKS-like 1 in lymph node-negative breast cancer.
Jonsdottir, K., Zhang, H., Jhagroe, D., Skaland, I., Slewa, A., Björkblom, B., Coffey, E., Gudlaugsson, E., Smaaland, R., Janssen, E. & Baak, J., juli 2012, I: Breast Cancer Research and Treatment.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
18 Citeringar (Scopus) -
2011
Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration.
Mai, A., Veltel, S., Pellinen, T., Padzik, A., Coffey, E., Marjomäki, V. & Ivaska, J., juli 2011, I: The Journal of cell biology.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
77 Citeringar (Scopus) -
Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate.
Westerlund, N., Zdrojewska, J., Padzik, A., Komulainen, E., Björkblom, B., Rannikko, E., Tararuk, T., Garcia-Frigola, C., Sandholm, J., Nguyen, L., Kallunki, T. & Coffey, E., feb. 2011, I: Nature Neuroscience.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
96 Citeringar (Scopus) -
2010
Activating transcription factor 3 is a positive regulator of human IFNG gene expression.
Filén, S., Ylikoski, E., Tripathi, S., West, A., Björkman, M., Nyström, J., Ahlfors, H., Coffey, E., Rao, K., Rasool, O. & Lahesmaa, R., mars 2010, I: Journal of immunology (Baltimore, Md. : 1950).Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
35 Citeringar (Scopus) -
AMPAR signaling mediating GABA(A)R delta subunit up-regulation in cultured mouse cerebellar granule cells.
Uusi-Oukari, M., Kontturi, L., Coffey, E. & Kallinen, S., maj 2010, I: Neurochemistry International.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
4 Citeringar (Scopus) -
Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation.
Podkowa, M., Zhao, X., Chow, C., Coffey, E., Davis, R. & Attisano, L., feb. 2010, I: Molecular and Cellular Biology.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
61 Citeringar (Scopus) -
The Vibrio parahaemolyticus Type III Secretion Systems manipulate host cell MAPK for critical steps in pathogenesis.
Matlawska-Wasowska, K., Finn, R., Mustel, A., O'Byrne, C., Baird, A., Coffey, E. & Boyd, A., dec. 2010, I: BMC Microbiology.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
47 Citeringar (Scopus) -
2009
Concurrent protective and destructive signaling of JNK2 in neuroblastoma cells.
Waetzig, V., Wacker, U., Haeusgen, W., Björkblom, B., Courtney, M., Coffey, E. & Herdegen, T., juni 2009, I: Cellular Signalling.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
12 Citeringar (Scopus) -
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.
Morfini, G., You, Y., Pollema, S., Kaminska, A., Liu, K., Yoshioka, K., Björkblom, B., Coffey, E., Bagnato, C., Han, D., Huang, C., Banker, G., Pigino, G. & Brady, S., juni 2009, I: Nature Neuroscience.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
222 Citeringar (Scopus) -
SCG10/STATHMIN-2 phosphorylation determines the rate of neuronal migration.
Coffey, E. & Zdrojewska, J., 23 aug. 2009.Forskningsoutput: Konferensbidrag › Sammanfattning › Vetenskaplig › Peer review
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2008
All JNKs can kill, but nuclear localization is critical for neuronal death.
Björkblom, B., Vainio, J., Hongisto, V., Herdegen, T., Courtney, M. & Coffey, E., maj 2008, I: The Journal of biological chemistry.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
77 Citeringar (Scopus) -
IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.
Johansen, L., Naumanen, T., Knudsen, A., Westerlund, N., Gromova, I., Junttila, M., Nielsen, C., Bøttzauw, T., Tolkovsky, A., Westermarck, J., Coffey, E., Jäättelä, M. & Kallunki, T., feb. 2008, I: Journal of Cell Science.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
87 Citeringar (Scopus) -
Loss-of-function of IKAP/ELP1: could neuronal migration defect underlie familial dysautonomia?
Naumanen, T., Johansen, L., Coffey, E. & Kallunki, T., okt. 2008, I: Cell adhesion & migration.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
18 Citeringar (Scopus) -
Superior cervical ganglion-10 protein as a molecular effector of c-Jun N-terminal kinase 1: implications for the therapeutic targeting of Jun N-terminal kinase in nerve regeneration.
Westerlund, N., Zdrojewska, J., Courtney, M. & Coffey, E., jan. 2008, I: Expert Opinion on Therapeutic Targets.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
5 Citeringar (Scopus) -
The Wnt pool of glycogen synthase kinase 3beta is critical for trophic-deprivation-induced neuronal death.
Hongisto, V., Vainio, J., Thompson, R., Courtney, M. & Coffey, E., jan. 2008, I: Molecular and Cellular Biology.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
30 Citeringar (Scopus) -
2007
JNK phosphorylates HMW-MAP2 PRD creating a binding motif for microtubules leading to regulation of process extension
Komulainen, E., Bjorkblom, B., Courtney, M. & Coffey, E., aug. 2007, I: Journal of Neurochemistry. 102, s. 274-274 1 s.Forskningsoutput: Tidskriftsbidrag › Mötesabstrakt › Peer review
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Rho mediates calcium-dependent activation of p38alpha and subsequent excitotoxic cell death.
Semenova, M., Mäki-Hokkonen, A., Cao, J., Komarovski, V., Forsberg, K., Koistinaho, M., Coffey, E. & Courtney, M., mars 2007, I: Nature Neuroscience.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
106 Citeringar (Scopus) -
2006
JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length
Tararuk, T., Ostman, N., Li, W., Björkblom, B., Padzik, A., Zdrojewska, J., Hongisto, V., Herdegen, T., Konopka, W., Courtney, M. J. & Coffey, E. T., 24 apr. 2006, I: Journal of Cell Biology. 173, 2, s. 265-77 13 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
150 Citeringar (Scopus) -
2005
Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector
Björkblom, B., Ostman, N., Hongisto, V., Komarovski, V., Filén, J.-J., Nyman, T. A., Kallunki, T., Courtney, M. J. & Coffey, E. T., 6 juli 2005, I: Journal of Neuroscience. 25, 27, s. 6350-61 12 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
145 Citeringar (Scopus) -
2004
Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death
Cao, J., Semenova, M. M., Solovyan, V. T., Han, J., Coffey, E. T. & Courtney, M. J., 20 aug. 2004, I: Journal of Biological Chemistry. 279, 34, s. 35903-13 11 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
101 Citeringar (Scopus) -
PSPN/GFRalpha4 has a significantly weaker capacity than GDNF/GFRalpha1 to recruit RET to rafts, but promotes neuronal survival and neurite outgrowth
Yang, J., Lindahl, M., Lindholm, P., Virtanen, H., Coffey, E., Runeberg-Roos, P. & Saarma, M., 2 juli 2004, I: FEBS Letters. 569, 1-3, s. 267-71 5 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
16 Citeringar (Scopus) -
2003
Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3
Hongisto, V., Smeds, N., Brecht, S., Herdegen, T., Courtney, M. J. & Coffey, E. T., sep. 2003, I: Molecular and Cellular Biology. 23, 17, s. 6027-36 10 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
132 Citeringar (Scopus) -
2002
c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons
Coffey, E. T., Smiciene, G., Hongisto, V., Cao, J., Brecht, S., Herdegen, T. & Courtney, M. J., 1 juni 2002, I: Journal of Neuroscience. 22, 11, s. 4335-45 11 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
171 Citeringar (Scopus)