FlowVision reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers

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FlowVision reveals key roles of flow dynamics and CD44-HA interaction in cancer cell arrest on endothelial monolayers

Gautier Follain1,2,3, Sujan Ghimire2*, Joanna W Pylvänäinen2,4*, Monika Vaitkevičiūtė1,2,4, Iván Hidalgo-Cenalmor2, Diana Wurzinger2, Camilo Guzmán5, James RW Conway6, Michal Dibus1, Jouni Härkönen1,7, Sanna Oikari8, Kirsi Rilla8, Marko Salmi4,9,10, Johanna Ivaska1,3,11-13#, Guillaume Jacquemet1,2,3,14#.





Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520 Turku, FI




Faculty of Science and Engineering, Cell Biology, Åbo Akademi University, FI-20520 Turku, FI




Turku Collegium for Science, Medicine and Technology (TCSMT), 20520 Turku, FI




InFLAMES Research Flagship Center, University of Turku and Åbo Akademi University, 20520 Turku, FI.




Euro-BioImaging ERIC, Turku, FI




Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, FI.




Department of Pathology, Hospital Nova of Central Finland, Well Being Services County of Central Finland, Jyväskylä, Finland




Institute of Biomedicine, University of Eastern Finland, 70211 Kuopio, FI




Institute of Biomedicine, University of Turku, Turku, FI




MediCity Research Laboratory, University of Turku, Turku, FI




Department of Life Technologies, University of Turku, 20520 Turku, FI.




Western Finnish Cancer Center (FICAN West), University of Turku, 20520 Turku, FI. 




Foundation for the Finnish Cancer Institute, Tukholmankatu 8, 00014 Helsinki, FI




Turku Bioimaging, University of Turku and Åbo Akademi University, FI- 20520 Turku, FI