Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Nobuyuki Tanaka; Shigeaki Kanatani; Raju Tomer; Cecilia Sahlgren; Pauliina Kronqvist; Dagmara Kaczynska; Lauri Louhivuori; Lorand Kis; Claes Lindh; Przemysław Mitura; Andrzej Stepulak; Sara Corvigno; Johan Hartman; Patrick Micke; Artur Mezheyeuski; Carina Strell; Joseph W. Carlson; Carlos Fernández Moro; Hanna Dahlstrand; Arne Östman; Kazuhiro Matsumoto; Peter Wiklund; Mototsugu Oya; Ayako Miyakawa; Karl Deisseroth; Per Uhlén

doi:10.1038/s41551-017-0139-0

Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Nobuyuki Tanaka
, Shigeaki Kanatani
, Raju Tomer
, Cecilia Sahlgren
, Pauliina Kronqvist
, Dagmara Kaczynska
, Lauri Louhivuori
, Lorand Kis
, Claes Lindh
, Przemysław Mitura
, Andrzej Stepulak
, Sara Corvigno
, Johan Hartman
, Patrick Micke
, Artur Mezheyeuski
, Carina Strell
, Joseph W. Carlson
, Carlos Fernández Moro
, Hanna Dahlstrand
, Arne Östman

Kazuhiro Matsumoto, Peter Wiklund, Mototsugu Oya, Ayako Miyakawa, Karl Deisseroth, Per Uhlén

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

154 Sitaatiot (Scopus)

Alkuperäiskieli	Ei tiedossa
Sivut	796–806
Julkaisu	Nature Biomedical Engineering
Numero	1
DOI - pysyväislinkit	https://doi.org/10.1038/s41551-017-0139-0
Tila	Julkaistu - 2017
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Rahoitus

This study was supported by the Swedish Research Council (grants 2009-3364, 2010-4392 and 2013-3189 to P.U.), the Swedish Cancer Society (grant CAN2013/802 and CAN2016/801 to P.U.), the Swedish Brain Foundation (grant FO2017/0107 to P.U.), the Linnaeus Center in Developmental Biology for Regenerative Medicine (DBRM) (P.U.), a Knut and Alice Wallenberg Foundation Grant to the Center for Live Imaging of Cells at the Karolinska (CLICK) Institutet (P.U.), the Royal Swedish Academy of Sciences (P.U.), the David and Astrid Hagelén Foundation (N.T.), the Takeda Science Foundation (N.T.), the Scandinavia-Japan Sasakawa Foundation (N.T. and S.K.), and the Wenner-Gren Foundation (S.K.). The light-sheet microscopy infrastructure used in this work received grants from the Strategic Research Area in Neuroscience – StratNeuro and the Strategic Research Area in Stem Cells and Regenerative Medicine – StratRegen supported by the Swedish government.

Pääsy asiakirjaan

10.1038/s41551-017-0139-0

Viittausmuodot

Tanaka, N., Kanatani, S., Tomer, R., Sahlgren, C., Kronqvist, P., Kaczynska, D., Louhivuori, L., Kis, L., Lindh, C., Mitura, P., Stepulak, A., Corvigno, S., Hartman, J., Micke, P., Mezheyeuski, A., Strell, C., Carlson, J. W., Fernández Moro, C., Dahlstrand, H., ... Uhlén, P. (2017). Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity. Nature Biomedical Engineering, (1), 796–806. https://doi.org/10.1038/s41551-017-0139-0

@article{48d9602ce58444878453684b768531d7,

title = "Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity",

author = "Nobuyuki Tanaka and Shigeaki Kanatani and Raju Tomer and Cecilia Sahlgren and Pauliina Kronqvist and Dagmara Kaczynska and Lauri Louhivuori and Lorand Kis and Claes Lindh and Przemys{\l}aw Mitura and Andrzej Stepulak and Sara Corvigno and Johan Hartman and Patrick Micke and Artur Mezheyeuski and Carina Strell and Carlson, \{Joseph W.\} and \{Fern{\'a}ndez Moro\}, Carlos and Hanna Dahlstrand and Arne {\"O}stman and Kazuhiro Matsumoto and Peter Wiklund and Mototsugu Oya and Ayako Miyakawa and Karl Deisseroth and Per Uhl{\'e}n",

year = "2017",

doi = "10.1038/s41551-017-0139-0",

language = "Odefinierat/ok{\"a}nt",

pages = "796–806",

journal = "Nature Biomedical Engineering",

issn = "2157-846X",

publisher = "Nature Research",

number = "1",

}

Tanaka, N, Kanatani, S, Tomer, R, Sahlgren, C, Kronqvist, P, Kaczynska, D, Louhivuori, L, Kis, L, Lindh, C, Mitura, P, Stepulak, A, Corvigno, S, Hartman, J, Micke, P, Mezheyeuski, A, Strell, C, Carlson, JW, Fernández Moro, C, Dahlstrand, H, Östman, A, Matsumoto, K, Wiklund, P, Oya, M, Miyakawa, A, Deisseroth, K & Uhlén, P 2017, 'Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity', Nature Biomedical Engineering, Nro 1, Sivut 796–806. https://doi.org/10.1038/s41551-017-0139-0

TY - JOUR

T1 - Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

AU - Tanaka, Nobuyuki

AU - Kanatani, Shigeaki

AU - Tomer, Raju

AU - Sahlgren, Cecilia

AU - Kronqvist, Pauliina

AU - Kaczynska, Dagmara

AU - Louhivuori, Lauri

AU - Kis, Lorand

AU - Lindh, Claes

AU - Mitura, Przemysław

AU - Stepulak, Andrzej

AU - Corvigno, Sara

AU - Hartman, Johan

AU - Micke, Patrick

AU - Mezheyeuski, Artur

AU - Strell, Carina

AU - Carlson, Joseph W.

AU - Fernández Moro, Carlos

AU - Dahlstrand, Hanna

AU - Östman, Arne

AU - Matsumoto, Kazuhiro

AU - Wiklund, Peter

AU - Oya, Mototsugu

AU - Miyakawa, Ayako

AU - Deisseroth, Karl

AU - Uhlén, Per

PY - 2017

Y1 - 2017

U2 - 10.1038/s41551-017-0139-0

DO - 10.1038/s41551-017-0139-0

M3 - Artikel

SN - 2157-846X

SP - 796

EP - 806

JO - Nature Biomedical Engineering

JF - Nature Biomedical Engineering

IS - 1

ER -