Tubulin polymerization inhibitors

Sanjeev Kumar Sahu; Manish Chaudhary; Shweta Jain; Kuldeep Kumar Bansal

doi:10.1016/B978-0-323-96121-9.00015-2

Tubulin polymerization inhibitors

Sanjeev Kumar Sahu
, Manish Chaudhary
, Shweta Jain
, Kuldeep Kumar Bansal

Tutkimustuotos: Artikkeli kirjassa/raportissa/konferenssijulkaisussa › Luku › Tieteellinen › vertaisarvioitu

Abstrakti

Tubulin polymerization is an essential phenomenon for the cell division process (mitosis). In cancer disease, there is a rapid or uncontrolled multiplication of cells, and this can be prevented by inhibition of microtubule formation that is inhibition of tubulin polymerization. In this chapter, microtubules, structure, and function along with the mechanism and domains of microtubules are discussed. In addition, based on domains or sites, various inhibitors of polymerization are also being discussed.

Alkuperäiskieli	Englanti
Otsikko	Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy
Kustantaja	Elsevier
Luku	15
Sivut	395-417
Sivumäärä	23
ISBN (elektroninen)	9780323961219
ISBN (painettu)	9780323961219, 9780323996327
DOI - pysyväislinkit	https://doi.org/10.1016/B978-0-323-96121-9.00015-2
Tila	Julkaistu - 2024
OKM-julkaisutyyppi	A3 Kirjan osa tai toinen tutkimuskirja

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10.1016/B978-0-323-96121-9.00015-2

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title = "Tubulin polymerization inhibitors",

abstract = "Tubulin polymerization is an essential phenomenon for the cell division process (mitosis). In cancer disease, there is a rapid or uncontrolled multiplication of cells, and this can be prevented by inhibition of microtubule formation that is inhibition of tubulin polymerization. In this chapter, microtubules, structure, and function along with the mechanism and domains of microtubules are discussed. In addition, based on domains or sites, various inhibitors of polymerization are also being discussed.",

keywords = "Colchicine, Hydrolysis, Microtubules, Mitosis, Tubulin, Vinblastine",

author = "Sahu, \{Sanjeev Kumar\} and Manish Chaudhary and Shweta Jain and Bansal, \{Kuldeep Kumar\}",

year = "2024",

doi = "10.1016/B978-0-323-96121-9.00015-2",

language = "English",

isbn = "9780323961219",

pages = "395--417",

booktitle = "Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy",

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TY - CHAP

T1 - Tubulin polymerization inhibitors

AU - Sahu, Sanjeev Kumar

AU - Chaudhary, Manish

AU - Jain, Shweta

AU - Bansal, Kuldeep Kumar

PY - 2024

Y1 - 2024

N2 - Tubulin polymerization is an essential phenomenon for the cell division process (mitosis). In cancer disease, there is a rapid or uncontrolled multiplication of cells, and this can be prevented by inhibition of microtubule formation that is inhibition of tubulin polymerization. In this chapter, microtubules, structure, and function along with the mechanism and domains of microtubules are discussed. In addition, based on domains or sites, various inhibitors of polymerization are also being discussed.

AB - Tubulin polymerization is an essential phenomenon for the cell division process (mitosis). In cancer disease, there is a rapid or uncontrolled multiplication of cells, and this can be prevented by inhibition of microtubule formation that is inhibition of tubulin polymerization. In this chapter, microtubules, structure, and function along with the mechanism and domains of microtubules are discussed. In addition, based on domains or sites, various inhibitors of polymerization are also being discussed.

KW - Colchicine

KW - Hydrolysis

KW - Microtubules

KW - Mitosis

KW - Tubulin

KW - Vinblastine

UR - https://www.scopus.com/pages/publications/85199020830

U2 - 10.1016/B978-0-323-96121-9.00015-2

DO - 10.1016/B978-0-323-96121-9.00015-2

M3 - Chapter

AN - SCOPUS:85199020830

SN - 9780323961219

SN - 9780323996327

SP - 395

EP - 417

BT - Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy

PB - Elsevier

ER -

Tubulin polymerization inhibitors

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