Simultaneous Determination of Ascorbic Acid, Dopamine and Uric Acid with Chitosan-Graphene Modified Electrode

Chitosan functionalized graphene was synthesized by a together-blending and in situ chemical reduction method. UV-vis, FT-IR, Raman and SEM techniques were used to study the molecular structure and morphology of the resulting composite. The chitosan-graphene modified glassy carbon electrode showed high electrocatalytic activity towards oxidations of ascorbic acid (AA), dopamine (DA) and uric acid (UA). By using the differential pulse voltammetry (DPV) as the analytical technique the calibration curves for AA, DA and UA, determined simultaneously, were found linear with a concentration range of 50–1200 μM, 1.0–24 μM and 2.0–45 μM, respectively.