Providing cellular signposts--post-translational modifications of intermediate filaments

Claire Hyder, Pallari, Vitaly Kochin, John Eriksson

    Tutkimustuotos: LehtiartikkeliKatsausartikkeliTieteellinenvertaisarvioitu

    62 Sitaatiot (Scopus)

    Abstrakti

    Intermediate filaments are dynamically regulated by their post-translational modifications. Initially these modifications were found to regulate filament dynamics and organization. In the last few years, their roles have extended significantly to facilitating, for example, the recruitment and sequestration of signaling molecules that regulate a wide range of cellular functions. While phosphorylation has been established as the principal post-translational modification regulating intermediate filament function, other modifications with co-operative roles are emerging, adding a further dimensions to intermediate filament-mediated signaling.
    AlkuperäiskieliEi tiedossa
    Sivut2140–2148
    JulkaisuFEBS Letters
    Vuosikerta582
    Numero14
    DOI - pysyväislinkit
    TilaJulkaistu - 2008
    OKM-julkaisutyyppiA2 Arvio tiedejulkaisuussa (artikkeli)

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