Protein unfolding versus β-sheet separation in spider silk nanocrystals

Parvez Alam, Nguyen Van Hieu (Toimittaja)

    Tutkimustuotos: LehtiartikkeliArtikkeliTieteellinenvertaisarvioitu

    15 Sitaatiot (Scopus)

    Abstrakti

    In this communication a mechanism for spider silk strain hardening is proposed. Shear failure of β-sheet nanocrystals is the first failure mode that gives rise to the creation of smaller nanocrystals, which are of higher strength and stiffness. β-sheet unfolding requires more energy than nanocrystal separation in a shear mode of failure. As a result, unfolding occurs after the nanocrystals separate in shear. β-sheet unfolding yields a secondary strain hardening effect once the β-sheet conformation is geometrically stable and acts like a unidirectional fibre in a fibre reinforced composite. The mechanism suggested herein is based on molecular dynamics calculations of residual inter-β-sheet separation strengths against residual intra-β-sheet unfolding strengths
    AlkuperäiskieliEi tiedossa
    Sivut
    JulkaisuAdvances in Natural Sciences: Nanoscience and Nanotechnology
    Vuosikerta5
    Numero1
    DOI - pysyväislinkit
    TilaJulkaistu - 2014
    OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

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